IGFBP3 Polyclonal Antibody

IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes Insulin-like growth factor-binding protein 3 with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

The IGFBP3 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of IGFBP3 protein in various biological samples. This antibody is produced using advanced techniques and is rigorously tested to ensure its high quality and reliability.

IGFBP3, also known as insulin-like growth factor-binding protein 3, is a key regulator of cell growth and development. It plays a crucial role in modulating the activity of insulin-like growth factors (IGFs) by binding to them and regulating their availability to target cells. IGFBP3 has been implicated in various physiological and pathological processes, including cancer, diabetes, and aging.

The IGFBP3 Polyclonal Antibody is generated by immunizing animals with a synthetic peptide corresponding to a specific region of the IGFBP3 protein. This antibody exhibits high affinity and specificity towards IGFBP3, enabling accurate and reliable detection of this protein in a wide range of sample types, including cell lysates, tissue homogenates, and serum.

This antibody is suitable for various applications, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). It has been validated for its performance in these assays and has shown excellent sensitivity and specificity. The IGFBP3 Polyclonal Antibody can be used for both qualitative and quantitative analysis of IGFBP3 protein expression, making it an invaluable tool for researchers studying the role of IGFBP3 in various biological processes.

In summary, the IGFBP3 Polyclonal Antibody is a highly reliable and specific tool for the detection and quantification of IGFBP3 protein. Its high quality and performance make it an essential reagent for researchers in the fields of cell biology, cancer research, and endocrinology.