IL-4R alpha(Phospho Tyr497) Polyclonal Antibody

This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.

The IL-4R alpha(Phospho Tyr497) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of IL-4R alpha protein phosphorylated at Tyr497. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity for the target protein.

IL-4R alpha is a crucial receptor involved in the signaling pathway of interleukin-4 (IL-4), a cytokine that plays a critical role in immune responses and inflammation. Phosphorylation of Tyr497 in IL-4R alpha has been shown to regulate its activity and downstream signaling events.

The IL-4R alpha(Phospho Tyr497) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated IL-4R alpha protein.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy handling and storage. The IL-4R alpha(Phospho Tyr497) Polyclonal Antibody is suitable for use in both research and clinical settings, facilitating the study of IL-4R alpha phosphorylation and its implications in various diseases and biological processes.

Choose the IL-4R alpha(Phospho Tyr497) Polyclonal Antibody for its exceptional performance, reliability, and versatility in detecting and quantifying phosphorylated IL-4R alpha protein. Experience accurate and reproducible results with this high-quality antibody, enabling advancements in the understanding of IL-4R alpha signaling and its role in immune regulation.