IL1RAP Polyclonal Antibody

IL1RAP Polyclonal Antibody

The IL1RAP Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Interleukin-1 receptor accessory protein (IL1RAP) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the IL1RAP protein.

IL1RAP is a transmembrane protein that plays a crucial role in the regulation of immune responses and inflammation. It acts as a co-receptor for the Interleukin-1 receptor family, including IL-1R1 and IL-1R3, and is involved in the activation of downstream signaling pathways. Dysregulation of IL1RAP expression has been implicated in various diseases, including autoimmune disorders, cancer, and inflammatory conditions.

The IL1RAP Polyclonal Antibody has been rigorously validated for its specificity and sensitivity. It exhibits minimal cross-reactivity with other related proteins, ensuring accurate and reliable results. This antibody is suitable for various applications, including Western blotting, immunohistochemistry, and flow cytometry.

In Western blotting, the IL1RAP Polyclonal Antibody recognizes a single band of the expected molecular weight, confirming its specificity. It can be used to detect endogenous IL1RAP protein in cell lysates or tissue extracts. In immunohistochemistry, this antibody enables the visualization of IL1RAP expression in formalin-fixed, paraffin-embedded tissue sections. It provides clear and distinct staining, allowing for the localization of IL1RAP within specific cell types or tissues.

Furthermore, the IL1RAP Polyclonal Antibody is compatible with flow cytometry, enabling the analysis of IL1RAP expression on the surface of cells. It can be used to identify and quantify IL1RAP-positive cell populations in heterogeneous samples.

Overall, the IL1RAP Polyclonal Antibody is a valuable tool for researchers studying the role of IL1RAP in various biological processes and diseases. Its high specificity, sensitivity, and versatility make it an essential component of any laboratory focused on immunological research.