Integrin alphaX Polyclonal Antibody

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.

The Integrin alphaX Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Integrin alphaX protein expression. This antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and flow cytometry.

Integrin alphaX is a transmembrane glycoprotein that plays a crucial role in cell adhesion and migration. It is primarily expressed on leukocytes, where it mediates cell-cell and cell-extracellular matrix interactions. Dysregulation of Integrin alphaX has been implicated in various pathological conditions, including inflammation, autoimmune diseases, and cancer.

Our Integrin alphaX Polyclonal Antibody has been developed using high-quality immunogens and state-of-the-art production techniques. It exhibits exceptional specificity and sensitivity, ensuring accurate and reproducible results. The antibody recognizes both the native and denatured forms of Integrin alphaX, making it suitable for a wide range of experimental settings.

In Western blotting, the Integrin alphaX Polyclonal Antibody demonstrates a strong and specific band at the expected molecular weight of Integrin alphaX. It can be used to detect endogenous levels of Integrin alphaX in various cell lysates and tissue extracts. Additionally, this antibody has been successfully employed in immunohistochemical staining of formalin-fixed, paraffin-embedded tissue sections, enabling the visualization of Integrin alphaX expression in situ.

Furthermore, the Integrin alphaX Polyclonal Antibody is compatible with flow cytometry analysis, allowing for the quantification and characterization of Integrin alphaX-positive cells in heterogeneous cell populations. It exhibits minimal background staining and provides reliable and reproducible results.

In summary, the Integrin alphaX Polyclonal Antibody is a valuable tool for researchers studying Integrin alphaX biology and its involvement in various physiological and pathological processes. Its high specificity, sensitivity, and versatility make it an essential component of any laboratory investigating cell adhesion, migration, and immune response.