IP3KA Polyclonal Antibody

Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.

The IP3KA Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the inositol 1,4,5-trisphosphate 3-kinase A (IP3KA) protein. The resulting polyclonal antibody is purified using protein A affinity chromatography to ensure high specificity and purity.

The IP3KA Polyclonal Antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been validated for use in human, mouse, and rat samples, making it a versatile tool for researchers working in a variety of fields.

This antibody has been shown to specifically recognize the IP3KA protein, which plays a critical role in the regulation of intracellular calcium signaling. The high specificity and sensitivity of the IP3KA Polyclonal Antibody make it an ideal tool for studying the function and regulation of this important protein.

Overall, the IP3KA Polyclonal Antibody is a reliable and effective tool for researchers looking to study the function and regulation of the IP3KA protein. Its high specificity and sensitivity make it a valuable addition to any research laboratory.