IRAK-1(Phospho Thr100) Polyclonal Antibody

This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

The IRAK-1(Phospho Thr100) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of IRAK-1 protein phosphorylated at threonine 100. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity for the target protein.

The IRAK-1 protein plays a crucial role in the innate immune response by mediating the signaling pathway downstream of Toll-like receptors (TLRs) and interleukin-1 receptors (IL-1Rs). Phosphorylation of IRAK-1 at threonine 100 is a key event in the activation of this protein and subsequent downstream signaling cascades.

This polyclonal antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated IRAK-1 protein in various biological samples.

The IRAK-1(Phospho Thr100) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and complex antibody preparation procedures. It is compatible with a wide range of experimental conditions and can be used in both research and clinical settings.

With its exceptional performance and reliability, the IRAK-1(Phospho Thr100) Polyclonal Antibody is an indispensable tool for researchers and clinicians studying the role of IRAK-1 in innate immunity and inflammatory diseases. Its high specificity and sensitivity make it an ideal choice for investigating the phosphorylation status of IRAK-1 and its functional implications in various biological processes.