JAK2(Phospho Tyr119) Polyclonal Antibody

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

The JAK2(Phospho Tyr119) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Janus kinase 2 (JAK2) protein phosphorylated at tyrosine 119 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the phosphorylated form of JAK2.

JAK2 is a crucial protein involved in the signal transduction pathway mediated by cytokine receptors. Phosphorylation of JAK2 at tyrosine 119 plays a significant role in the activation and regulation of downstream signaling cascades, ultimately influencing various cellular processes such as proliferation, differentiation, and survival.

The JAK2(Phospho Tyr119) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate detection and quantification of phosphorylated JAK2 in complex biological samples.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, ensuring cost-effectiveness and minimizing wastage. The JAK2(Phospho Tyr119) Polyclonal Antibody is compatible with a wide range of experimental conditions and can be used in diverse research areas, including cancer biology, immunology, and signal transduction studies.

With its superior performance and reliability, the JAK2(Phospho Tyr119) Polyclonal Antibody is an indispensable tool for researchers aiming to investigate the role of JAK2 phosphorylation in cellular processes and disease pathogenesis.