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ELK Biotechnology
SKU(재고 관리 코드):ES9082
KAT6B Rabbit Polyclonal Antibody
KAT6B Rabbit Polyclonal Antibody
KAT6B Rabbit Polyclonal Antibody
Overview
| Product name: | KAT6B rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 1170-1250 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 228kD |
| GeneID（Human）: | 23522 |
| Human Swiss-Prot No: | Q8WYB5 |
| Cellular localization: | Nucleus . |
| Background: | The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012], |
| Species Reactivity: | Human;Mouse |
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