KI2S5 Polyclonal Antibody

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the

The KI2S5 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of KI2S5 protein expression in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a unique epitope of the KI2S5 protein.

The KI2S5 Polyclonal Antibody exhibits exceptional affinity and selectivity towards the target protein, ensuring accurate and reliable results in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

With its superior sensitivity, this antibody allows for the detection of even low levels of KI2S5 protein expression, making it an invaluable tool for researchers studying the role of KI2S5 in various cellular processes and disease mechanisms.

Furthermore, the KI2S5 Polyclonal Antibody has been rigorously tested for its specificity, ensuring minimal cross-reactivity with other proteins, thereby minimizing false-positive results.

This product is supplied as a liquid formulation, ready for immediate use, and is available in various sizes to accommodate different experimental needs. Each batch of the KI2S5 Polyclonal Antibody undergoes stringent quality control measures to guarantee consistent performance and reproducibility.

In summary, the KI2S5 Polyclonal Antibody is a reliable and efficient tool for the detection and analysis of KI2S5 protein expression, offering researchers a valuable resource to advance their scientific investigations.