KIR3.1 Polyclonal Antibody

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein KCNJ3, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, ataxia, and Parkinson's disease. Alternative splicing results in multiple transcript variants encoding distinct proteins.

The KIR3.1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of KIR3.1 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target protein.

The KIR3.1 Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and minimal cross-reactivity, enabling accurate and reliable results.

This antibody is manufactured under strict quality control measures, ensuring batch-to-batch consistency and reproducibility. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation.

The KIR3.1 Polyclonal Antibody is suitable for use in both research and clinical settings, facilitating the investigation of KIR3.1 protein expression in normal and diseased tissues. Its versatility and reliability make it an indispensable tool for scientists and clinicians studying the role of KIR3.1 in various physiological and pathological processes.

Choose the KIR3.1 Polyclonal Antibody for its exceptional performance, reliability, and ease of use, and unlock new insights into the function and regulation of KIR3.1 protein.