LC3 A/B Rabbit Polyclonal Antibody

Probably involved in formation of autophagosomal vacuoles (autophagosomes).|PTM:The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form| LC3-I. This is activated by APG7L/ATG7| transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form| LC3-II.|Belongs to the MAP1 LC3 family.|subcellular location:LC3-II binds to the autophagic membranes.|subunit:3 different light chains| LC1| LC2 and LC3| can associate with MAP1A and MAP1B proteins.|tissue specificity:Most abundant in heart| brain| liver| skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.|

The LC3 A/B Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of LC3 A and LC3 B proteins in various biological samples. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring exceptional sensitivity and specificity.

LC3 A and LC3 B are key autophagy-related proteins that play crucial roles in the regulation of autophagy, a cellular process involved in the degradation and recycling of cellular components. The LC3 A/B Rabbit Polyclonal Antibody recognizes both LC3 A and LC3 B isoforms, allowing for comprehensive analysis of autophagy-related processes.

This antibody has been extensively validated for various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent performance in detecting endogenous LC3 A and LC3 B proteins in a wide range of species, including human, mouse, and rat.

The LC3 A/B Rabbit Polyclonal Antibody offers exceptional sensitivity, enabling the detection of low-abundance LC3 A and LC3 B proteins. Its high specificity ensures minimal cross-reactivity with other proteins, resulting in accurate and reliable results.

With its superior quality and performance, the LC3 A/B Rabbit Polyclonal Antibody is an indispensable tool for researchers studying autophagy and its associated processes. It provides valuable insights into the regulation and function of LC3 A and LC3 B proteins, contributing to a better understanding of cellular homeostasis and disease mechanisms.

Order the LC3 A/B Rabbit Polyclonal Antibody today and enhance your research capabilities in the field of autophagy.