LC3A Rabbit Polyclonal Antibody

Probably involved in formation of autophagosomal vacuoles (autophagosomes).|PTM:The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form| LC3-I. This is activated by APG7L/ATG7| transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form| LC3-II.|Belongs to the MAP1 LC3 family.|subcellular location:LC3-II binds to the autophagic membranes.|subunit:3 different light chains| LC1| LC2 and LC3| can associate with MAP1A and MAP1B proteins.|tissue specificity:Most abundant in heart| brain| liver| skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.|

The LC3A Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of LC3A protein expression in various biological samples. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring exceptional performance and reliability.

LC3A, also known as microtubule-associated protein 1 light chain 3 alpha, plays a crucial role in autophagy, a cellular process involved in the degradation and recycling of cellular components. The LC3A Rabbit Polyclonal Antibody recognizes the LC3A protein, allowing for the investigation of autophagy-related processes in a wide range of research areas, including cancer, neurodegenerative diseases, and metabolic disorders.

This antibody has been extensively validated for its specificity and sensitivity, ensuring accurate and reproducible results. It exhibits minimal cross-reactivity with other LC3 isoforms, ensuring reliable detection of LC3A protein expression specifically. The LC3A Rabbit Polyclonal Antibody is suitable for various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

With its high affinity and specificity, the LC3A Rabbit Polyclonal Antibody offers researchers a valuable tool for studying autophagy and its implications in various biological processes. Its exceptional performance and reliability make it an ideal choice for scientists seeking to unravel the intricate mechanisms underlying autophagy-related diseases and pathways.