The antiserum was produced against synthesized peptide derived from human STK10. AA range:491-540
Storage:
Rabbit
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
120kD
GeneID（Human）:
6793
Human Swiss-Prot No:
O94804
Cellular localization:
Cell membrane ; Peripheral membrane protein .
Background:
This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008],
Western Blot analysis of various cells using LOK Polyclonal Antibody
Western Blot analysis of HuvEc cells using LOK Polyclonal Antibody
Western blot analysis of the lysates from HT-29 cells using STK10 antibody.
Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).