MAN1B1 Polyclonal Antibody

MAN1B1 encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11.

The MAN1B1 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of MAN1B1 protein expression. This antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The MAN1B1 Polyclonal Antibody is produced using state-of-the-art techniques, ensuring high affinity and specificity. It has been rigorously tested to ensure minimal cross-reactivity with other proteins, guaranteeing accurate and reliable results.

This antibody is suitable for use in a wide range of species, including human, mouse, and rat, making it versatile and applicable to various research areas. It is supplied as a liquid formulation, allowing for easy and convenient handling.

With its exceptional sensitivity and specificity, the MAN1B1 Polyclonal Antibody is an indispensable tool for researchers studying the role of MAN1B1 in various biological processes. Its high-quality performance and reliability make it an ideal choice for both basic research and clinical applications.