MARCKS(Phospho Ser163) Polyclonal Antibody

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

The MARCKS(Phospho Ser163) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated Serine 163 residue of the Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) protein. This antibody is produced using advanced immunization techniques, resulting in a high affinity and specificity towards the phosphorylated Ser163 epitope.

MARCKS is a key regulatory protein involved in various cellular processes, including actin cytoskeleton remodeling, membrane trafficking, and signal transduction. Phosphorylation of Ser163 residue plays a crucial role in the modulation of MARCKS function and its interaction with other cellular components. Therefore, the MARCKS(Phospho Ser163) Polyclonal Antibody serves as an invaluable tool for researchers studying the role of MARCKS in cellular processes and signaling pathways.

This antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunofluorescence, and immunohistochemistry. It exhibits minimal cross-reactivity with non-phosphorylated Ser163 residue and other related proteins, ensuring accurate and reliable results.

The MARCKS(Phospho Ser163) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy integration into various experimental protocols. The antibody is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

In summary, the MARCKS(Phospho Ser163) Polyclonal Antibody is a highly specific and sensitive tool that enables researchers to investigate the phosphorylation status of Ser163 residue in the MARCKS protein. Its exceptional performance and reliability make it an essential reagent for studies focused on understanding the molecular mechanisms underlying cellular processes and signaling pathways involving MARCKS.