This antibody is specific to a protein of 20 kDa known as MART-1 (melanoma antigen recognized by T cells-1) or Melan-A. This antibody does not crossreact with MAGE-1or tyrosinase. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. This antibody stains melanomas and other tumors showing melanocytic differentiation.
