MDHC Polyclonal Antibody

This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6.

The MDHC Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the human MDHC protein. The resulting polyclonal antibody has been purified using a combination of protein A and protein G chromatography to ensure high purity and specificity.

The MDHC Polyclonal Antibody has been extensively validated for use in Western blotting, immunohistochemistry, and immunofluorescence assays. It has been shown to specifically recognize the MDHC protein in a variety of human tissues and cell lines. This antibody has also been shown to be highly sensitive, with a detection limit of as low as 0.1 ng/mL.

In addition to its high specificity and sensitivity, the MDHC Polyclonal Antibody is also highly versatile. It can be used in a variety of applications, including basic research, drug discovery, and clinical diagnostics. Its high quality and reliability make it an ideal choice for researchers and clinicians who require accurate and reproducible results.

Overall, the MDHC Polyclonal Antibody is a valuable tool for researchers and clinicians who are studying the MDHC protein and its role in various biological processes. Its high specificity, sensitivity, and versatility make it an essential component of any research or diagnostic program.