MITF(Phospho Ser180) Polyclonal Antibody

This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

The MITF(Phospho Ser180) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of MITF protein phosphorylated at Serine 180. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

MITF, also known as microphthalmia-associated transcription factor, plays a crucial role in the regulation of melanocyte development and differentiation. Phosphorylation of MITF at Serine 180 has been implicated in various cellular processes, including melanogenesis, cell cycle progression, and apoptosis.

The MITF(Phospho Ser180) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated MITF protein in various biological samples.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing wastage. The antibody is compatible with a wide range of experimental conditions and can be used in both research and clinical settings.

With its exceptional performance and reliability, the MITF(Phospho Ser180) Polyclonal Antibody is an indispensable tool for researchers and clinicians studying the role of MITF phosphorylation in melanocyte biology and related diseases.