MMP-14 Polyclonal Antibody

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by MMP14 is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

The MMP-14 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of matrix metalloproteinase-14 (MMP-14) in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards MMP-14.

Matrix metalloproteinases (MMPs) are a family of enzymes that play a crucial role in the degradation and remodeling of the extracellular matrix. Among them, MMP-14, also known as membrane-type 1 matrix metalloproteinase (MT1-MMP), has been implicated in various physiological and pathological processes, including tissue remodeling, angiogenesis, and cancer metastasis.

The MMP-14 Polyclonal Antibody exhibits exceptional sensitivity and specificity, making it an ideal choice for researchers and clinicians involved in studying MMP-14-related processes and diseases. This antibody has been extensively validated in various experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence.

With its superior performance, the MMP-14 Polyclonal Antibody enables accurate and reliable detection of MMP-14 in a wide range of sample types, including cell lysates, tissue homogenates, and biological fluids. Its high specificity ensures minimal cross-reactivity with other MMP family members, allowing for precise quantification of MMP-14 expression levels.

Furthermore, the MMP-14 Polyclonal Antibody is manufactured under strict quality control standards, ensuring batch-to-batch consistency and reproducibility. Each lot is rigorously tested to meet the highest standards of quality, purity, and performance.

In summary, the MMP-14 Polyclonal Antibody is a valuable tool for researchers and clinicians seeking to investigate the role of MMP-14 in various biological processes and diseases. Its exceptional sensitivity, specificity, and reliability make it an indispensable asset in the field of matrix metalloproteinase research.