This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013],
Western Blot analysis of various cells using MMP-19 Polyclonal Antibody diluted at 1:500
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using MMP-19 Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from HUVEC cells, using MMP-19 Antibody. The lane on the right is blocked with the synthesized peptide.