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SKU(재고 관리 코드):MAA540Ge22

Monoclonal Antibody to Corticosterone (Cort)

Monoclonal Antibody to Corticosterone (Cort)

UOM
Concentration
Organism species

Immunohistochemistry: 5-20µg/mL;1:50-200
;Immunocytochemistry: 5-20µg/mL;1:50-200
;Optimal working dilutions must be determined by end user.

Product No.

MAA540Ge22

Organism Species

Pan-species (General).

Source

Monoclonal antibody preparation

Host

Mouse

Potency (Clone Number)

8#

Ig Isotype

IgG1 Kappa

Purification

Protein A + Protein G affinity chromatography

Label

None

Immunogen

CPA540Ge21-OVA Conjugated Corticosterone (Cort)

Buffer Formulation

0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Traits

Liquid

Concentration

1mg/mL

Organism Species More

n/a

Applications

ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a mouse monoclonal antibody raised against Cort. It has been selected for its ability to recognize Cort in immunohistochemical staining and western blotting.

USAGE

Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

Respir Res.

Intracerebroventricular injection of leukotriene B4 attenuates antigen-induced asthmatic response via BLT1 receptor stimulating HPA-axis in sensitized rats. PubMed: 20403205

Natural Product Sciences

Effects of Gypenosides on Acute Stress in Mice Papersearch: Source

Neuropeptides.?

Role of adrenomedullin in the cerebrospinal fluid-contacting nucleus in the modulation of immobilization stress Pubmed:25911494

EXPERIMENTAL & CLINICAL CARDIOLOGY

Sick Sinus Syndrome May Attribute to the Decrease of ?±-klotho Protein in Mice Com:Source

Journal of Pharmacological Sciences

Organ-Specific Activation of the Gastric Branch of the Efferent Vagus Nerve by Ghrelin in Urethane-Anesthetized Rats Pubmed:24366191

Toxicology Letters

Regulation of corticosterone secretion is modified by PFOS exposure at different levels of the hypothalamic–pituitary–adrenal axis in adult male rats Pubmed:24440345

Stress.

Restraint stress alters immune parameters and induces oxidative stress in the mouse uterus during embryo implantation Pubmed:25238024

Int J Clin Exp Med

Diabetes alters the blood glucose response to ketamine in streptozotocin-diabetic rats PubMed: 26379948

Pakistan Veterinary Journal

Trivalent Chromium Attenuated Corticosterone Secretion and Actions in Adrenocorticotropic Hormone-Stimulated Rats In_Press: 15-058.Pdf

BMC

Ameliorating effects of gypenosides on chronic stress-induced anxiety disorders in mice PubMed: 26370834

Behav Brain Res

Rats with differential self-grooming expression in the elevated plus-maze do not differ in anxiety-related behaviors PubMed: 26142783

Archives of Physiology and Biochemistry

Improvement of oral contraceptive-induced glucose dysreCavia (Guinea pig )lation and dyslipidemia by valproic acid is independent of circulating corticosterone Pubmed:26855320

Archives of Physiology and Biochemistry

Activation of cardiac renin–angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder Pubmed:26934364

Neuroscience Letters

Electroacupuncture reCavia (Guinea pig )late hypothalamic–pituitary–adrenal axis and enhance hippocampal serotonin system in a rat model of depression Pubmed:26773866

Neural Regeneration Research

Moxibustion upreCavia (Guinea pig )lates hippocampal progranulin expression. Pubmed:27212922

Environmental Science and Pollution Research

Lycopene ameliorates atrazine-induced oxidative damage in adrenal cortex of male rats by activation of the Nrf2/HO-1 pathway Pubmed:27102619

Eur Neuropsychopharmacol

Apelin-13 exerts antidepressant-like and recognition memory improving activities in stressed rats Pubmed:26853763

experimental brain research

Dopamine D2-like receptors modulate freezing response, but not the activation of HPA axis, during the expression of conditioned fear. pubmed:27766352

brain research bulletin

Activation of ATP-sensitive potassium channel by iptakalim normalizes stress-induced HPA axis disorder and depressive behaviour by alleviating inflammation and oxidative stress in mouse hypothalamus. pubmed:28161195

Neurochemical Research 

Effects of (-)-Sesamin on Chronic Stress-Induced Anxiety Disorders in Mice pubmed:27995494

Journal of Molecular Histology

Role of serotonin in the intestinal mucosal epithelium barrier in weaning mice undergoing stress-induced diarrhea pubmed:29260435

Psychosomatic Medicine

The Role of Psychological Stress on Heart Autophagy in Mice With Heart Failure pubmed:28691995

Scientific Reports COMMUNICATIONS

Environmental perturbation of the circadian clock during pregnancy leads to transgenerational mood disorder-like behaviors in mice pubmed:28974783

BMC Gastroenterology

Role of serotonin on the intestinal mucosal immune response to stress-induced diarrhea in weaning mice pubmed:28633646

biorxiv

Anxiety-like but not despair-like behaviors are further aggravated by chronic mild stress in the early stages of APPswe/PS1dE9 transgenic mice doi.org/10.1101/202283

Frontiers in Molecular Neuroscience

Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis. pubmed:28959186

Biochemical Pharmacology

Effects of n-3 PUFA enriched and n-3 PUFA deficient diets in naïve and Aβ-treated female rats Pubmed:30028991

Toxicological Sciences

Impact of Perfluorooctane Sulfonate on Reproductive Ability of Female Mice through Suppression of Estrogen Receptor a-Activated Kisspeptin Neurons 10.1093:toxsci

Nutrition

Multigenerational effects of dietary macronutrients intake on the metabolic phenotype of male Wistar rats 10.1016:j.nut.2018.06.008

Behavioural Brain Research

Depressive-and anxiety-like phenotypes in young adult APPSwe/PS1dE9 transgenic mice with insensitivity to chronic mild stress Pubmed:30012417

Stress

Blockade of AT1 type receptors for angiotensin II prevents cardiac microvascular fibrosis induced by chronic stress in Sprague–Dawley rats Pubmed:29676198

Inflammation

Differential Effects of Brain Death on Rat Microcirculation and Intestinal Inflammation: Female Male Pubmed:29737476

Respiratory physiology & neurobiology

Curcumin attenuates chronic intermittent hypoxia-induced brain injuries by inhibiting AQP4 and p38 MAPK pathway Pubmed:29758366

Nature and Science of Sleep

Chronic treatment with dexamethasone alters clock gene expression and melatonin synthesis in rat pineal gland at night Pubmed:30046256

Journal of Pharmacy and Pharmacology

Tannins from fruits attenuates GABA antagonist‐induced anxiety‐like behaviour modulation of neurotransmitters Pubmed: 30198561

Bulletin of Experimental Biology and Medicine

Expression of Hif-1α, Nf-κb, and Vegf Genes in the Liver and Blood Serum Levels of HIF-1α, Erythropoietin, VEGF, TGF-β, 8-Isoprostane, and Corticosterone in Wistar Rats with High and Low Resistance to Hypoxia. Corticosterone in … Pubmed: 30353332

Brain, Behavior, and Immunity

HMGB1-Mediated Differential Response on Hippocampal Neurotransmitter Disorder and Neuroinflammation in Adolescent Male and Female Mice following Cold Exposure Pubmed: 30476565

Heliyon

Establishment and evaluation of a novel mouse model of peri/postmenopausal depression Doi: 10.1016/j.heliyon.2019.e01195

Scientific Reports

Mice lacking Casp1, Ifngr and Nos2 genes exhibit altered depressive-and anxiety-like behaviour, and gut microbiome composition Pubmed: 31015500

Food & Function

Antidepressant-like effects of dietary gardenia blue pigment derived from genipin and tyrosine Doi: 10.1039/C9FO00480G

Neuroscience Letters

Synaptic structure and alterations in the hippocampus in neonatal rats exposed to lipopolysaccharide Pubmed: 31288048

FASEB Journal

Contribution of DNA methylation in chronic stress–induced cardiac remodeling and arrhythmias in mice Pubmed: 31431066

Cells

MicroRNA-99a is a Potential Target for Regulating Hypothalamic Synaptic Plasticity in the Peri/Postmenopausal Depression Model Pubmed: 31540304

endocrine journal

Mice with nucleus tractus solitarius injury induced by chronic restraint stress present impaired ability to raise blood glucose and glucagon levels when blood glucose … Pubmed: 32249244

INTERNATIONAL IMMUNOPHARMACOLOGY

GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and … Pubmed: 33166810

neurochemical research

Anxiolytic and Anti‑depressive Like Effects of Translocator Protein (18 kDa) Ligand YL‑IPA08 in a Rat Model of Postpartum Depression Pubmed: 32383026

BioMed Research International

Pathophysiological Changes in Female Rats with Estrous Cycle Disorder Induced by Long-Term Heat Stress Pubmed: 32685488

博士论文

Neurobiological determinants of depressive-like symptoms in rodents

Behavioral Ecology and Sociobiology 

Exposure to eagle owl feces induces anti-predator behavior, physiology, and hypothalamic gene responses in a subterranean rodent, the plateau zokor (Eospalax …

Ther Adv Chronic Dis

Empagliflozin improves chronic hypercortisolism-induced abnormal myocardial structure and cardiac function in mice 33294147

International Journal of?Nanomedicine

Water-Soluble Carbon Dots in Cigarette Mainstream Smoke: Their Properties and the Behavioural, Neuroendocrinological, and Neurotransmitter Changes They ¡­ 33762821

CRYOBIOLOGY

O-GlcNAc/Akt pathway regulates glucose metabolism and reduces apoptosis in liver of piglets with acute cold stress 33651993

NEUROSCIENCE RESEARCH

Sleep disturbance induces depressive behaviors and neuroinflammation by altering the circadian oscillations of clock genes in rats 33785408

Biomed Res Int

A Famous Chinese Medicine Formula: Yinhuo Decoction Antagonizes the Damage of Corticosterone to PC12 Cells and Improves Depression by Regulating … Pubmed:35281603

Ecotoxicol Environ Saf

Monochromatic blue light not green light exposure is associated with continuous light-induced hepatic steatosis in high fat diet fed-mice via oxidative stress Pubmed:35588616


Catalog No.

Related products for research use of Pan-species (General) Organism species

Applications (RESEARCH USE ONLY!)

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ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).

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WB; IHC; ICC; IF.

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ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).

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ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).

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ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).

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WB; IHC; ICC.

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ELISA Kit for Corticosterone (Cort)

Enzyme-linked immunosorbent assay for Antigen Detection.

WEA540Ge

Wide-range ELISA Kit for Corticosterone (Cort)

Enzyme-linked immunosorbent assay for Antigen Detection.

MEA540Ge

Mini Samples ELISA Kit for Corticosterone (Cort)

Enzyme-linked immunosorbent assay for Antigen Detection.

CCA540Ge

CLIA Kit for Corticosterone (Cort)

Chemiluminescent immunoassay for Antigen Detection.

LMA540Ge

Magnetic Luminex Assay Kit for Corticosterone (Cort) ,etc.

Magnetic Luminex Assay for Antigen Detection.

KSA540Ge11

ELISA Kit DIY Materials for Corticosterone (Cort)

Main materials for "Do It (ELISA Kit) Yourself".

 

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