Cloud-clone
SKU(재고 관리 코드):MAC918Hu22
Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21)
Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21)
Western blotting: 0.5-5ug/ml
;Immunocytochemistry in formalin fixed cells: 5-30ug/ml
;Immunohistochemistry in formalin fixed frozen section: 5-30ug/ml
;Immunohistochemistry in paraffin section: 5-30ug/ml
;Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
;Optimal working dilutions must be determined by end user.
Product No.
MAC918Hu22
Organism Species
Homo sapiens (Human).
Source
Monoclonal antibody preparation
Host
Mouse
Potency (Clone Number)
C4
Ig Isotype
IgG2b Kappa
Purification
Protein A + Protein G affinity chromatography
Label
None
Immunogen
RPC918Hu01-Recombinant Fibroblast Growth Factor 21 (FGF21)
Buffer Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Traits
Liquid
Concentration
1mg/ml
Organism Species More
n/a
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a mouse monoclonal antibody raised against FGF21. It has been selected for its ability to recognize FGF21 in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Magazine |
Citations |
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Lipids in Health and Disease |
Dietary moderately oxidized oil induces expression of fibroblast growth factor 21 in the liver of pigs Lipidworld: source |
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Endocrinology |
Orphan nuclear receptor Nur77 mediates fasting-induced hepatic fibroblast growth factor 21 expression Endocrine:Source |
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Biochemical and Biophysical Research Communications |
Alpha lipoic acid induces hepatic fibroblast growth factor 21 expression via up-regulation of CREBH Pubmed:25449271 |
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Free Radic Biol Med |
Skeletal muscle increases FGF21 expression in mitochondrial disorders to compensate for energy metabolic insufficiency by activating the mTOR–YY1–PGC1α pathway PubMed: 25843656 |
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Journal of diabetes and its complications |
Associations between FGF21, osteonectin and bone turnover markers in type 2 diabetic patients with albuminuria. pubmed:27916484 |
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American journal of the medical sciences |
Association of Bone Metabolic Markers With Diabetic Retinopathy and Diabetic Macular Edema in Elderly Chinese Individuals With Type 2 Diabetes Mellitus pubmed:29078839 |
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Frontiers in Physiology |
Ileal Transposition Surgery Decreases Fat Mass and Improves Glucose Metabolism in Diabetic GK Rats: Possible Involvement of FGF21 Pubmed:29593555 |
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Некоторые аспекты транспортной системы метаболизма железа в зависимости от степени синдрома перегрузки железом у детей с хроническим … |
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Physiol Res |
Fibroblast growth factor 21 (FGF21) in children and adolescents with chronic kidney disease. Pubmed: 32469231 |
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Chinese Journal of Osteoporosis |
2 型糖尿病患者血清FGF21, 骨连结蛋白和骨转换指标的相关性研究. |
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Sci Rep |
Ileal transposition helps to regulate plasma hepatokine levels in obese Zucker (Crl: ZUC (ORL)-Lepr fa) rats 33833309 |
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Nutrients |
The Speed of Ingestion of a Sugary Beverage Has an Effect on the Acute Metabolic Response to Fructose |
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Medicine (Baltimore) |
Association of serum fibroblast growth factor 21 with kidney function in a population-based Chinese cohort 34918690 |
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Annals of Agricultural and Environmental Medicine |
Oxidative stress-induced growth inhibitor 1 in alcohol-induced liver cirrhosis 34969228 |
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J Magn Reson Imaging |
Water Specific MRI T1 Mapping for Evaluating Liver Inflammation Activity Grades in Rats With Methionine‐Choline‐Deficient Diet‐Induced Nonalcoholic Fatty Liver … Pubmed:35212074 |
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Lab Invest |
Fibroblast growth factor 21, a stress regulator, inhibits Drp1 activation to alleviate skeletal muscle ischemia/reperfusion injury Pubmed:35488034 |
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Molecular Biology Reports |
Umbilical cord-derived mesenchymal stem cell conditioned medium reverses neuronal oxidative injury by inhibition of TRPM2 activation and the JNK signaling … Pubmed:35585377 |
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High Circulating Fibroblast Growth Factor-21 Levels as a Prognostic Marker in Fatty Pancreas Patients |
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Catalog No. |
Related products for research use of Homo sapiens (Human) Organism species |
Applications (RESEARCH USE ONLY!) |
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RPC918Hu01 |
Positive Control; Immunogen; SDS-PAGE; WB. |
|
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APC918Hu61 |
Cell culture; Activity Assays. |
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EPC918Hu61 |
Positive Control; Immunogen; SDS-PAGE; WB. |
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APC918Hu01 |
Cell culture; Activity Assays. |
|
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PAC918Hu01 |
WB; IHC; ICC; IP. |
|
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FAC918Hu01 |
Anti-Fibroblast Growth Factor 21 (FGF21) Polyclonal Antibody |
Flow cytometry. |
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MAC918Hu21 |
WB; IHC; ICC; IP. |
|
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MAC918Hu23 |
WB; IHC; ICC; IP. |
|
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MAC918Hu24 |
WB; IHC; ICC; IP. |
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MAC918Hu22 |
WB; IHC; ICC; IP. |
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SEC918Hu |
Enzyme-linked immunosorbent assay for Antigen Detection. |
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MEC918Hu |
Mini Samples ELISA Kit for Fibroblast Growth Factor 21 (FGF21) |
Enzyme-linked immunosorbent assay for Antigen Detection. |
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SCC918Hu |
Chemiluminescent immunoassay for Antigen Detection. |
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CCC918Hu |
Chemiluminescent immunoassay for Antigen Detection. |
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LMC918Hu |
Magnetic Luminex Assay Kit for Fibroblast Growth Factor 21 (FGF21) ,etc. |
Magnetic Luminex Assay for Antigen Detection. |
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