제품 정보로 건너뛰기
1 1

Cloud-clone

SKU(재고 관리 코드):MAC918Hu22

Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21)

Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21)

UOM
Concentration
Organism species

Western blotting: 0.5-5ug/ml
;Immunocytochemistry in formalin fixed cells: 5-30ug/ml
;Immunohistochemistry in formalin fixed frozen section: 5-30ug/ml
;Immunohistochemistry in paraffin section: 5-30ug/ml
;Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
;Optimal working dilutions must be determined by end user.

Product No.

MAC918Hu22

Organism Species

Homo sapiens (Human).

Source

Monoclonal antibody preparation

Host

Mouse

Potency (Clone Number)

C4

Ig Isotype

IgG2b Kappa

Purification

Protein A + Protein G affinity chromatography

Label

None

Immunogen

RPC918Hu01-Recombinant Fibroblast Growth Factor 21 (FGF21)

Buffer Formulation

PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Traits

Liquid

Concentration

1mg/ml

Organism Species More

n/a

Applications

WB; IHC; ICC; IP.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a mouse monoclonal antibody raised against FGF21. It has been selected for its ability to recognize FGF21 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

Lipids in Health and Disease

Dietary moderately oxidized oil induces expression of fibroblast growth factor 21 in the liver of pigs Lipidworld: source

Endocrinology

Orphan nuclear receptor Nur77 mediates fasting-induced hepatic fibroblast growth factor 21 expression Endocrine:Source

Biochemical and Biophysical Research Communications

Alpha lipoic acid induces hepatic fibroblast growth factor 21 expression via up-regulation of CREBH Pubmed:25449271

Free Radic Biol Med

Skeletal muscle increases FGF21 expression in mitochondrial disorders to compensate for energy metabolic insufficiency by activating the mTOR–YY1–PGC1α pathway PubMed: 25843656

Journal of diabetes and its complications

Associations between FGF21, osteonectin and bone turnover markers in type 2 diabetic patients with albuminuria. pubmed:27916484

American journal of the medical sciences

Association of Bone Metabolic Markers With Diabetic Retinopathy and Diabetic Macular Edema in Elderly Chinese Individuals With Type 2 Diabetes Mellitus pubmed:29078839

Frontiers in Physiology

Ileal Transposition Surgery Decreases Fat Mass and Improves Glucose Metabolism in Diabetic GK Rats: Possible Involvement of FGF21 Pubmed:29593555


Некоторые аспекты транспортной системы метаболизма железа в зависимости от степени синдрома перегрузки железом у детей с хроническим …

Physiol Res

Fibroblast growth factor 21 (FGF21) in children and adolescents with chronic kidney disease. Pubmed: 32469231

Chinese Journal of Osteoporosis

2 型糖尿病患者血清FGF21, 骨连结蛋白和骨转换指标的相关性研究.

Sci Rep

Ileal transposition helps to regulate plasma hepatokine levels in obese Zucker (Crl: ZUC (ORL)-Lepr fa) rats 33833309

Nutrients

The Speed of Ingestion of a Sugary Beverage Has an Effect on the Acute Metabolic Response to Fructose

Medicine (Baltimore)

Association of serum fibroblast growth factor 21 with kidney function in a population-based Chinese cohort 34918690

Annals of Agricultural and Environmental Medicine

Oxidative stress-induced growth inhibitor 1 in alcohol-induced liver cirrhosis 34969228

J Magn Reson Imaging

Water Specific MRI T1 Mapping for Evaluating Liver Inflammation Activity Grades in Rats With Methionine‐Choline‐Deficient Diet‐Induced Nonalcoholic Fatty Liver … Pubmed:35212074

Lab Invest

Fibroblast growth factor 21, a stress regulator, inhibits Drp1 activation to alleviate skeletal muscle ischemia/reperfusion injury Pubmed:35488034

Molecular Biology Reports

Umbilical cord-derived mesenchymal stem cell conditioned medium reverses neuronal oxidative injury by inhibition of TRPM2 activation and the JNK signaling … Pubmed:35585377


High Circulating Fibroblast Growth Factor-21 Levels as a Prognostic Marker in Fatty Pancreas Patients


Catalog No.

Related products for research use of Homo sapiens (Human) Organism species

Applications (RESEARCH USE ONLY!)

RPC918Hu01

Recombinant Fibroblast Growth Factor 21 (FGF21)

Positive Control; Immunogen; SDS-PAGE; WB.

APC918Hu61

Active Fibroblast Growth Factor 21 (FGF21)

Cell culture; Activity Assays.

EPC918Hu61

Eukaryotic Fibroblast Growth Factor 21 (FGF21)

Positive Control; Immunogen; SDS-PAGE; WB.

APC918Hu01

Active Fibroblast Growth Factor 21 (FGF21)

Cell culture; Activity Assays.

PAC918Hu01

Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21)

WB; IHC; ICC; IP.

FAC918Hu01

Anti-Fibroblast Growth Factor 21 (FGF21) Polyclonal Antibody

Flow cytometry.

MAC918Hu21

Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21)

WB; IHC; ICC; IP.

MAC918Hu23

Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21)

WB; IHC; ICC; IP.

MAC918Hu24

Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21)

WB; IHC; ICC; IP.

MAC918Hu22

Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21)

WB; IHC; ICC; IP.

SEC918Hu

ELISA Kit for Fibroblast Growth Factor 21 (FGF21)

Enzyme-linked immunosorbent assay for Antigen Detection.

MEC918Hu

Mini Samples ELISA Kit for Fibroblast Growth Factor 21 (FGF21)

Enzyme-linked immunosorbent assay for Antigen Detection.

SCC918Hu

CLIA Kit for Fibroblast Growth Factor 21 (FGF21)

Chemiluminescent immunoassay for Antigen Detection.

CCC918Hu

CLIA Kit for Fibroblast Growth Factor 21 (FGF21)

Chemiluminescent immunoassay for Antigen Detection.

LMC918Hu

Magnetic Luminex Assay Kit for Fibroblast Growth Factor 21 (FGF21) ,etc.

Magnetic Luminex Assay for Antigen Detection.

 

전체 세부 정보 보기