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Cloud-clone
SKU(재고 관리 코드):MAA222Hu22
Monoclonal Antibody to Interferon Beta (IFNb)
Monoclonal Antibody to Interferon Beta (IFNb)
Western blotting: 0.5-2µg/mL;
;Immunohistochemistry: 5-20µg/mL;
;Immunocytochemistry: 5-20µg/mL;
;Optimal working dilutions must be determined by end user.
;Immunohistochemistry: 5-20µg/mL;
;Immunocytochemistry: 5-20µg/mL;
;Optimal working dilutions must be determined by end user.
Product No.
MAA222Hu22
Organism Species
Homo sapiens (Human).
Source
Monoclonal antibody preparation
Host
Mouse
Potency (Clone Number)
C13
Ig Isotype
IgG2b Kappa
Purification
Protein A + Protein G affinity chromatography
Label
None
Immunogen
RPA222Hu01-Recombinant Interferon Beta (IFNb)
Buffer Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Traits
Liquid
Concentration
1mg/ml
Organism Species More
Sus scrofa; Porcine (Pig)
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a mouse monoclonal antibody raised against IFNb. It has been selected for its ability to recognize IFNb in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| 20 | Melatonin protects liver against ischemia and reperfusion injury through inhibition of toll-like receptor signaling pathway PubMed: 21355876 |
| Journal of General Virology | Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKKε and DDX3. Sgm: 9182080 |
| Biochemical and Biophysical Research Communications | Impaired TLR3/IFN-β signaling in monocyte-derived dendritic cells from patients with acute-on-chronic hepatitis B liver failure: Relevance to the severity of liver damage ScienceDirect: S0006291X09019822 |
| PLoS One | Intact Type I Interferon Production and IRF7 Function in Sooty Mangabeys PubMed: PMC3757038 |
| PLoS Neglected Tropical Diseases | Innate Immune Response to Rift Valley Fever Virus in Goats PubMed: PMC3335883 |
| BioMed Research International | Low pH Environmental Stress Inhibits LPS and LTA-Stimulated Proinflammatory Cytokine Production in Rat Alveolar Macrophages Pubmed: 24288685 |
| Vet Microbiol. | An attenuated EIAV strain and its molecular clone strain differentially induce the expression of Toll-like receptors and type-I interferons in equine monocyte-derived macrophages. Pubmed: 23850441 |
| Food and Chemical Toxicology | Scoparone attenuates d-galactosamine/lipopolysaccharide-induced fulminant hepatic failure through inhibition of toll-like receptor 4 signaling in mice Pubmed: 23535186 |
| Veterinary immunology and immunopathology | Experimental model of equine alveolar macrophage stimulation with TLR ligands Pubmed: 23815824 |
| American journal of respiratory cell and molecular biology | Training Modifies Innate Immune Responses in Blood Monocytes and in Pulmonary Alveolar Macrophages Pubmed: 24502337 |
| FEBS Lett. | Mannan binding lectin attenuates double-stranded RNA-mediated TLR3 activation and innate immunity Pubmed:24530528 |
| Veterinary Research | Infection of equine monocyte-derived macrophages with an attenuated equine infectious anemia virus (EIAV) strain induces a strong resistance to the infection by a virulent EIAV strain Pubmed:25106750 |
| PLOS Neglected Tropical Diseases | MicroRNA-30e* Suppresses Dengue Virus Replication by Promoting NF-κB–Dependent IFN Production Pubmed:25122182 |
| Veterinary Research | The innate immune response of equine bronchial epithelial cells is altered by training Pubmed:25595212 |
| molecular and celluar biology | SOCS3 Drives Proteasomal Degradation of TBK1 and Negatively Regulates Antiviral Innate Immunity PubMed: 25939384 |
| Arch Virol | Analysis of cytokine production in a newly developed canine tracheal epithelial cell line infected with H3N3 canine influenza virus PubMed: 25797196 |
| J | Complexes of DNA with the Antimicrobial Peptide LL37 Augment NK Cell Functions by Inducing Type I Interferon Production from Circulating Monocytes and Plasmacytoid Predendritic Cells PubMed: 26258404 |
| Virus | PKR activation enhances replication of classical swine fever virus in PK-15 cells PubMed: 25899421 |
| PLoS One | siRNA Targeting the 2A pro Genomic Region Prevents Enterovirus 71 Replication In Vitro Pubmed:26886455 |
| Scientific Reports | Cellular uptake of exogenous calcineurin B is dependent on TLR4/MD2/CD14 complexes, and CnB is an endogenous ligand of TLR4 Pubmed:27090571 |
| Front Microbiol | Innate Immune Responses in ALV-J Infected Chicks and Chickens with Hemangioma In Vivo Pubmed:27252695 |
| Canadian Journal of Physiology and Pharmacology | Chloroquine attenuates lipopolysaccharide-induced inflammatory responses through upregulation of USP25. pubmed:28134560 |
| International Journal of Molecular Medicine | Effects of IRF1 and IFN-β interaction on the M1 polarization of macrophages and its antitumor function pubmed:27176664 |
| International Journal of Clinical and Experimental Pathology | Host miR-146a promotes replication of human cytomegalovirus by suppressing type I IFN response in MRC-5 cells files:ijcep0036479.pdf |
| Poultry Science | ALV-J strain SCAU-HN06 induces innate immune responses in chicken primary monocyte-derived macrophages pubmed:27486255 |
| Journal of Virology | Characterization of Simian Immunodeficiency Virus Variants Anatomically Compartmentalized inPlasma and Milk in Chronically Infected African Green Monkeys. pubmed: |
| Biochemical and Biophysical Research Communications | MicroRNA-548j inhibits type I interferon production by targeting ZBTB11 in patients with chronic hepatitis B pubmed:28342861 |
| Virology | The down-regulation of casein kinase 1 alpha as a host defense response against infectious bursal disease virus infection pubmed:28988058 |
| EMBO Journal | Zika virus elicits inflammation to evade antiviral response by cleaving cGAS via NS1‐caspase‐1 axis Pubmed:30065070 |
| Toxicology and applied pharmacology | Bisphenol A induced male germ cell apoptosis via IFNβ-XAF1-XIAP pathway in adult mice Pubmed:30017639 |
| Archives of Virology | MAVS induces a host cell defense to inhibit CSFV infection Pubmed:29556776 |
| Journal of virology | Inhibition of DNA-sensing pathway by Marek's disease virus VP23 protein through suppression of interferon regulatory factor 7 activation Pubmed: 30518647 |
| Veterinary Immunology and Immunopathology | Molecular cloning and functional characterization of porcine 2′, 5′-oligoadenylate synthetase 1b and its effect on infection with porcine reproductive and respiratory?… Doi: 10.1016/j.vetimm.2019.01.003 |
| Science Signaling | HIPK2 is necessary for type I interferon–mediated antiviral immunity Doi: 10.1126/scisignal.aau4604 |
| INTERNATIONAL MEDICAL RESEARCH | Evaluation of serum interferons in patients with age-related macular degeneration Pubmed: 31007694 |
| Veterinary Immunology and Immunopathology | Differential expression of type I interferon mRNA and protein levels induced by virulent Marek's disease virus infection in chickens |
| International journal of biological macromolecules | Porcine FcγRIIb mediated PRRSV ADE infection through inhibiting IFN-β by cytoplasmic inhibitory signal transduction Pubmed: 31284005 |
| Journal of virology | Marek's Disease Virus RLORF4 Inhibits Type I Interferon Production by Antagonizing NF-κB Activation Pubmed: 31243133 |
| The Journal of Latvian Academy of Sciences | Serodiagnosis of Human Bocavirus 1 Infection among Hospitalised Children with Lower Respiratory Tract Infection in Latvia |
| Cancer Medicine | The immunostimulatory effects and pro‐apoptotic activity of rhCNB against Lewis lung cancer is mediated by Toll‐like receptor 4 Pubmed: 31218844 |
| FASEB Journal | Scavenger receptor A impairs interferon response to HBV infection by limiting TRAF 3 ubiquitination through recruiting OTUB 1 |
| PLOS Pathogens | Avian oncogenic herpesvirus antagonizes the cGAS-STING DNA-sensing pathway to mediate immune evasion Pubmed: 31539404 |
| Autophagy | Induction of autophagy and suppression of type I IFN secretion by CSFV Pubmed: 32160078 |
| MOLECULAR IMMUNOLOGY | BVDV-1 induces interferon-beta gene expression through a pathway involving IRF1, IRF7, and NF-κB activation Pubmed: 33053462 |
| Autophagy | LDHB inhibition induces mitophagy and facilitates the progression of CSFV infection Pubmed: 32924761 |
| Arch Virol . | Infectious bronchitis virus inhibits activation of the TLR7 pathway, but not the TLR3 pathway Pubmed: 32532134 |
| Virulence | Determination of antiviral action of Long Non-coding RNA loc107051710 During Infectious Bursal Disease Virus Infection due to Enhancement of Interferon … |
| bioRxiv | Transferrin-dependent crosstalk between the intestinal tract and commensal microbes contributes for immune tolerance |
| Res Vet Sci | Open reading frame 5 protein of porcine circovirus type 2 induces RNF128 (GRAIL) which inhibits mRNA transcription of interferon-β in porcine epithelial cells 34416463 |
| Eur J Immunol | Anti‐IFN‐α/‐ω neutralizing antibodies from COVID‐19 patients correlate with downregulation of IFN response and laboratory biomarkers of disease severity Pubmed:35419822 |
| ResearchSquare | Chicken Intestinal Microbiota Modulation of Resistance to Nephropathogenic Infectious Bronchitis Virus Infection Through IFN-I |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| APA222Hu02 | Active Interferon Beta (IFNb) | Cell culture; Activity Assays. |
| RPA222Hu02 | Recombinant Interferon Beta (IFNb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA222Hu01 | Active Interferon Beta (IFNb) | Cell culture; Activity Assays. |
| RPA222Hu01 | Recombinant Interferon Beta (IFNb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA222Hu01 | Polyclonal Antibody to Interferon Beta (IFNb) | WB; IHC; ICC; IP. |
| PAA222Hu02 | Polyclonal Antibody to Interferon Beta (IFNb) | WB; IHC; ICC; IP. |
| MAA222Hu22 | Monoclonal Antibody to Interferon Beta (IFNb) | WB; IHC; ICC; IP. |
| MAA222Hu21 | Monoclonal Antibody to Interferon Beta (IFNb) | WB,IHC |
| MAA222Hu23 | Monoclonal Antibody to Interferon Beta (IFNb) | WB; IHC; ICC; IP. |
| MAA222Hu24 | Monoclonal Antibody to Interferon Beta (IFNb) | WB; IHC; ICC; IP. |
| MAA222Hu25 | Monoclonal Antibody to Interferon Beta (IFNb) | WB; IHC; ICC; IP. |
| MAA222Hu26 | Monoclonal Antibody to Interferon Beta (IFNb) | WB; IHC; ICC; IP. |
| MAA222Hu27 | Monoclonal Antibody to Interferon Beta (IFNb) | WB; IHC; ICC; IP. |
| SEA222Hu | ELISA Kit for Interferon Beta (IFNb) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| MEA222Hu | Mini Samples ELISA Kit for Interferon Beta (IFNb) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| AEA222Hu | ELISA Kit for Anti-Interferon Beta Antibody (Anti-IFNb) | Enzyme-linked immunosorbent assay for Antibody Detection. |
| LMA222Hu | Magnetic Luminex Assay Kit for Interferon Beta (IFNb) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
| KSA222Hu01 | ELISA Kit DIY Materials for Interferon Beta (IFNb) | Main materials for "Do It(ELISA Kit) Yourself" |
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