Cloud-clone
SKU(재고 관리 코드):MAC580Hu22
Monoclonal Antibody to Lysyl Oxidase (LOX)
Monoclonal Antibody to Lysyl Oxidase (LOX)
Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.
Product No.
MAC580Hu22
Organism Species
Homo sapiens (Human).
Source
Monoclonal antibody preparation
Host
Mouse
Potency (Clone Number)
n/a
Ig Isotype
IgG
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Label
None
Immunogen
n/a
Buffer Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Traits
Liquid
Concentration
1mg/mL
Organism Species More
n/a
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a mouse monoclonal antibody raised against LOX. It has been selected for its ability to recognize LOX in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Magazine |
Citations |
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American Journal of Hematology |
The expression of lysyl-oxidase gene family members in myeloproliferative neoplasms. PubMed: 23494965 |
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Current Eye Research |
High Glucose Induced Differential Expression of Lysyl Oxidase and Its Isoform in ARPE-19 Cells Pubmed: 22966818 |
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European Journal of Surgical Oncology |
Evaluation of serum lysyl oxidase as a blood test for colorectal cancer Pubmed: 24246612 |
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Vaccine |
Copia autorizada por CDR Ingentaconnect: Source |
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Arthritis & Rheumatology |
Lysyl oxidase is a potential biomarker of fibrosis in systemic sclerosis Pubmed: 24574233 |
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Eur J Surg Oncol.? |
Evaluation of serum lysyl oxidase as a blood test for colorectal cancer Pubmed:Pmc4237001 |
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BMC Cancer. |
Ionizing radiation induces tumor cell lysyl oxidase secretion Pubmed:Pmc4223762 |
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DNA Cell Biol. |
Lysyl Oxidase Genetic Variants Affect Gene Expression in Cervical Cancer Pubmed:24945327 |
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scandinavian journal of immunology |
Increased Serum Levels of the IL-33 Neutralizing sST2 in Limited Cutaneous Systemic Sclerosis PubMed: 26095613 |
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Curr Eye Res |
Correlation of Aqueous Humor Lysyl Oxidase Activity with TGF-ß Levels and LOXL1 Genotype in Pseudoexfoliation Pubmed:27116380 |
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journal of bone and mineral metabolism |
LOX Fails to Substitute for RANKL in Osteoclastogenesis. pubmed:27606829 |
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38 |
Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases. pubmed:28445728 |
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Molecular Medicine Reports |
Lysyl oxidase is involved in synovial hyperplasia and angiogenesis in rats with collagen‑induced arthritis pubmed:28901438 |
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Revista Española de Cardiología (English Edition) |
A Global Assessment of Circulating Prolysyl Oxidase in Nonischemic Patients With Garden-variety Heart Failure With Preserved Ejection Fraction Pubmed:29807761 |
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Molecular Medicine Reports |
Lysyl oxidase inhibition via β-aminoproprionitrile hampers human umbilical vein endothelial cell angiogenesis and migration in vitro Pubmed:29393489 |
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Thyroid |
Lysyl Oxidase is a key player in BRAF/MAPK pathway-driven thyroid cancer aggressiveness Pubmed: 30398411 |
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Am J Physiol Lung Cell Mol Physiol |
Lysyl Oxidase Directly Contributes to Extracellular Matrix Production and Fibrosis in Systemic Sclerosis. Pubmed: 33026236 |
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J Am Heart Assoc |
Collagen Cross©\Linking Is Associated With Cardiac Remodeling in Hypertrophic Obstructive Cardiomyopathy 33356379 |
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