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Cloud-clone
SKU(재고 관리 코드):MAA756Hu22
Monoclonal Antibody to Mucin 5 Subtype AC (MUC5AC)
Monoclonal Antibody to Mucin 5 Subtype AC (MUC5AC)
Western blotting: 0.5-2µg/mL;
;Immunohistochemistry: 5-20µg/mL;
;Immunocytochemistry: 5-20µg/mL;
;Optimal working dilutions must be determined by end user.
;Immunohistochemistry: 5-20µg/mL;
;Immunocytochemistry: 5-20µg/mL;
;Optimal working dilutions must be determined by end user.
Product No.
MAA756Hu22
Organism Species
Homo sapiens (Human).
Source
Monoclonal antibody preparation
Host
Mouse
Potency (Clone Number)
C8
Ig Isotype
IgG2b Kappa
Purification
Protein A + Protein G affinity chromatography
Label
None
Immunogen
RPA756Hu01-Recombinant Mucin 5 Subtype AC (MUC5AC)
Buffer Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Traits
Liquid
Concentration
1mg/ml
Organism Species More
Sus scrofa; Porcine (Pig)
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a mouse monoclonal antibody raised against MUC5AC. It has been selected for its ability to recognize MUC5AC in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Annals of surgical oncology | Pancreatic cyst fluid and serum mucin levels predict dysplasia in intraductal papillary mucinous neoplasms of the pancreas. PubMed: 20717734 |
| Investigative Ophthalmology & Visual Science | Entrapment of Conjunctival Goblet Cells by Desiccation-Induced Cornification PubMed: 21421863 |
| Cell & Molecular Biology | Role of aquaporin 5 in antigen-induced airway inflammation and mucous hyperproduction in mice PubMed: 20550619 |
| Mucosal Immunology | Homeostatic control of conjunctival mucosal goblet cells by NKT-derived IL-13 Nature: 201082a |
| European Journal of Pharmacology | Naringin attenuates EGF-induced MUC5AC secretion in A549 cells by suppressing the cooperative activities of MAPKs-AP-1 and IKKs-IκB-NF-κB signaling pathways ScienceDirect: S0014299912005523 |
| PLoS One | Baicalein Reduces Airway Injury in Allergen and IL-13 Induced Airway Inflammation PubMed: PMC3639905 |
| Respiratory Researh | Pyocyanin-induced mucin production is associated with redox modification of FOXA2 PubMed: PMC3765780 |
| Surgery | A novel serum marker for biliary tract cancer: Diagnostic and prognostic values of quantitative evaluation of serum mucin 5AC (MUC5AC) Pubmed: 24468034 |
| Biochemical and Biophysical Research Communications | The human cathelicidin LL-37 enhances airway mucus production in chronic obstructive pulmonary disease Pubmed:24291709 |
| Journal of Proteomics | Proteomic analysis of cancer and mesothelial cells reveals an increase in Mucin 5AC during ovarian cancer and peritoneal interaction Pubmed:24726482 |
| Experimental Lung Research | The human Cathelicidin LL-37 induces MUC5AC mucin production by airway epithelial cells via TACE-TGF-α-EGFR pathway Pubmed:24901072 |
| Surgery.? | Assessment of bile and serum mucin5AC in cholangiocarcinoma: Diagnostic performance and biologic significance Pubmed:25151557 |
| Allergology International | Leukotriene E 4 induces MUC5AC release from human airway epithelial NCI-H292 cells Pubmed:25838093 |
| Respirology | Secreted mucins and airway bacterial colonization in non-CF bronchiectasis PubMed: 26172851 |
| S | Isabela Casagrande Jeremias Teses: Disponiveis |
| American Thoracic Society International Conference Abstracts | Mucin Secretion In Asthmatics With Osmotic Airway Hyperresponsiveness doi:10.1164 |
| Deletion Polymorphism and Chronic Obstructive Pulmonary Disease | ReCavia (Guinea pig )lation of Viral Infection-induced Airway Remodeling Cytokine Production by the TLR3-EGFR Signaling Pathway in Human Bronchial Epithelial Cells Pubmed:27075970 |
| Int J Clin Exp Med | The influence of long-term corneal contact lens wearing on the stability and quality of tear film in Qinghai files:ijcem0020163.pdf |
| Ann Am Thorac Soc | Airway Mucin 2 Is Decreased in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization doi:10.1513 |
| Sci Rep | Impact of Cigarette Smoking on Tear Function and Correlation between Conjunctival Goblet Cells and Tear MUC5AC Concentration in Office Workers Pubmed:27297822 |
| Cytokine. | Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasalepithelial cells. pubmed:27776277 |
| J Virol. | Mutating the CX3C Motif in the G Protein Should Make a Live Respiratory Syncytial Virus Vaccine Safer and More Effective. pubmed:28275196 |
| Respiratory Physiology & Neurobiology | Peroxiredoxin 6 suppresses Muc5ac overproduction in LPS-induced airway inflammation through H2O2-EGFR-MAPK signaling pathway. pubmed:27884794 |
| Journal of Immunology Research | Beneficial effects of prebiotic Saccharomyces cerevisiae mannan on allergic asthma mouse models pubmed:28835901 |
| BASIC INVESTIGATION | Efficacy of Sodium Hyaluronate in Murine Diabetic Ocular Surface Diseases pubmed:28644234 |
| International Immunopharmacology | Clarithromycin inhibits TNF-α-induced MUC5AC mucin gene expression via the MKP-1-p38MAPK-dependent pathway pubmed:28550735 |
| Секреторно-экссудативная реакция слизистой носа на воздействие холодного воздуха у больных бронхиальной астмой 10.20538/1682-0363-2017-2-146-158 | |
| Cellular Microbiology | An adherent mucus layer attenuates the genotoxic effect of colibactin. pubmed:29156489 |
| Respiratory Research | IL-4-induced caveolin-1-containing lipid rafts aggregation contributes to MUC5AC synthesis in bronchial epithelial cells pubmed:28931396 |
| Chemotherapy | Oxytetracycline Inhibits Mucus Secretion and Inflammation in Human Airway Epithelial Cells. pubmed:28578323 |
| Allergy | Th2 cytokines orchestrate the secretion of MUC 5 AC and MUC 5B in IL‐5 positive chronic rhinosinusitis with nasal polyps Pubmed:29802623 |
| European Journal of Pharmacology | Salvianolic acid B improves airway hyperresponsiveness by inhibiting MUC5AC overproduction associated with Erk1/2/P38 signaling Pubmed:29382534 |
| Inflammation | Plantamajoside Inhibits Lipopolysaccharide-Induced MUC5AC Expression and Inflammation through Suppressing the PI3K/Akt and NF-κB Signaling Pathways in … Pubmed:29349683 |
| Pulmonary Pharmacology and Therapeutics | In vivo and in vitro investigation of anti-inflammatory and mucus-regulatory activities of a fixed combination of thyme and primula extracts Pubmed:29698781 |
| European Respiratory Society | Profiling of healthy and asthmatic airway smooth muscle cells following IL-1β treatment: a novel role for CCL20 in chronic mucus hyper-secretion Pubmed:29946002 |
| Clinical and Experimental Ophthalmology | Development of a highly sensitive and reliable enzyme-linked immunosorbent assay for MUC5aC in human tears extracted from schirmer strips Pubmed: 30214141 |
| international journal of biological macromolecules | Increased expression of long non-coding RNA SNHG16 correlates with tumor progression and poor prognosis in non-small cell lung cancer Pubmed: 30287374 |
| Journal of Investigative Medicine | The characteristics and clinical significance of mucin levels in bronchoalveolar lavage fluid of patients with interstitial lung disease Pubmed: 30573494 |
| Phytomedicine | Regulation effects of naringin on diesel particulate matter-induced abnormal airway surface liquid secretion Pubmed: 31301536 |
| Scientific Reports | Regional comparison of Goblet cell number and Area in exposed and covered Dry eyes and their Correlation with Tear MUC5AC Pubmed: 32076085 |
| Eur J Pharmacol | TLR3 inhibitor and tyrosine kinase inhibitor attenuate cigarette smoke/poly I: C-induced airway inflammation and remodeling by the EGFR/TLR3/MAPK … Pubmed: 33068589 |
| journal of ethnopharmacology | Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K … Pubmed: 32344236 |
| Less Airway Inflammation and Goblet Cell Metaplasia in an IL-33-Induced Asthma Model of Leptin-Deficient Obese Mice | |
| Exp Mol Pathol | The regulatory role of SFRP5/WNT5A axis in allergic rhinitis through inhibiting JNK pathway activation and lowering mucin generation in human nasal?¡ 33285209 |
| FEBS Open Bio | Porphyromonas gingivalis gingipains potentially affect MUC5AC gene expression and protein levels in respiratory epithelial cells 33332733 |
| Cell Rep | Generation of functional conjunctival epithelium, including goblet cells, from human iPSCs 33535050 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| RPA756Hu01 | Recombinant Mucin 5 Subtype AC (MUC5AC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA756Hu01 | Polyclonal Antibody to Mucin 5 Subtype AC (MUC5AC) | WB; IHC; ICC; IP. |
| LAA756Hu81 | FITC-Linked Polyclonal Antibody to Mucin 5 Subtype AC (MUC5AC) | WB; IHC; ICC; IF. |
| LAA756Hu71 | Biotin-Linked Polyclonal Antibody to Mucin 5 Subtype AC (MUC5AC) | WB; IHC; ICC. |
| MAA756Hu21 | Monoclonal Antibody to Mucin 5 Subtype AC (MUC5AC) | WB |
| MAA756Hu22 | Monoclonal Antibody to Mucin 5 Subtype AC (MUC5AC) | WB; IHC; ICC; IP. |
| LAA756Hu72 | Biotin-Linked Monoclonal Antibody to Mucin 5 Subtype AC (MUC5AC) | WB; IHC; ICC. |
| SEA756Hu | ELISA Kit for Mucin 5 Subtype AC (MUC5AC) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA756Hu | CLIA Kit for Mucin 5 Subtype AC (MUC5AC) | Chemiluminescent immunoassay for Antigen Detection. |
| LMA756Hu | Magnetic Luminex Assay Kit for Mucin 5 Subtype AC (MUC5AC) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
| PSA756Hu01 | Antibody Pair for Mucin 5 Subtype AC (MUC5AC) | ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays. |
| KSA756Hu01 | ELISA Kit DIY Materials for Mucin 5 Subtype AC (MUC5AC) | Main materials for "Do It (ELISA Kit) Yourself". |
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