Cloud-clone
SKU(재고 관리 코드):MAC842Hu22
Monoclonal Antibody to Secreted Frizzled Related Protein 5 (SFRP5)
Monoclonal Antibody to Secreted Frizzled Related Protein 5 (SFRP5)
Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.
Product No.
MAC842Hu22
Organism Species
Homo sapiens (Human).
Source
Monoclonal antibody preparation
Host
Mouse
Potency (Clone Number)
n/a
Ig Isotype
IgG
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Label
None
Immunogen
n/a
Buffer Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Traits
Liquid
Concentration
1mg/mL
Organism Species More
Mus musculus (Mouse), Rattus norvegicus (Rat)
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a mouse monoclonal antibody raised against SFRP5. It has been selected for its ability to recognize SFRP5 in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Magazine |
Citations |
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Diabetes Research and Clinical Practice |
Plasma SFRP5 levels are decreased in Chinese subjects with obesity and type 2 diabetes and negatively correlated with parameters of insulin resistance PubMed: 23290274 |
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European Journal of Clinical Investigation |
Sfrp5 correlates with insulin resistance and oxidative stress PubMed: 23398169 |
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Pediatric Research |
Balanced duo of anti-inflammatory SFRP5 and proinflammatory WNT5A in children Pubmed: 24603290 |
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Clin Endocrinol (Oxf). |
SFRP5 correlates with obesity and metabolic syndrome and increases after weight loss in children Pubmed: 24330025 |
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The Journal of Clinical Endocrinology & Metabolism |
Circulating Sfrp5 is a signature of obesity-related metabolic disorders and is regulated by glucose and liraglutide in humans Pubmed: 23185036 |
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Atherosclerosis |
Low serum level of secreted frizzled-related protein 5, an anti-inflammatory adipokine, is associated with coronary artery disease Pubmed: 24530778 |
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PLoS One. |
Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation Pubmed:Pmc4072672 |
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J Clin Endocrinol Metab. |
Activation of noncanonical Wnt signaling through WNT5A in visceral adipose tissue of obese subjects is related to inflammation Pubmed:24840810 |
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Oncology Letters |
Serum secreted frizzled?related protein 5 levels differentially decrease in patients with hepatitis B virus?associated chronic infection and hepatocellular carcinoma Pubmed:25120720 |
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Diabetes Metab Res Rev. |
Circulating SFRP5 levels are elevated in drug‐na?ve recently diagnosed type 2 diabetic patients as compared with prediabetic subjects and controls Pubmed:25139699 |
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Clinical & Experimental Immunology |
The wingless-related integration site-5a/secreted frizzled-related protein-6 system is dysregulated in human sepsis Pubmed:25382802 |
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Diabetes Metab Res Rev |
Circulating SFRP5 levels are elevated in drug-na PubMed: 25139699 |
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J Matern Fetal Neonatal Med |
Prediction of gestational diabetes mellitus by first trimester serum secreted frizzle-related protein-5 levels PubMed: 26100762 |
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Eur J Clin Invest |
Sfrp5 associates with beta-cell function in humans Pubmed:27019073 |
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Osteoporosis International |
Bone marrow sFRP5 level is negatively associated with bone formation markers pubmed:27986984 |
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Diabetes/Metabolism Research and Reviews |
Plasma Sfrp5 levels correlate with determinants of the metabolic syndrome in Chinese adults pubmed:28303637 |
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Cardiovascular Diabetology |
Inverse associations between serum levels of secreted frizzled-related protein-5 (SFRP5) and multiple cardiometabolic risk factors: KORA F4 study pubmed:28851362 |
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Arteriosclerosis, Thrombosis, and Vascular Biology |
Effect of SFRP5 (Secreted Frizzled–Related Protein 5) on the WNT5A (Wingless-Type Family Member 5A)-Induced Endothelial Dysfunction and Its Relevance With … Pubmed:29674475 |
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Obesity |
Longitudinal Increases in Adiposity Contribute to Worsening Adipokine Profile over Time in Mexican Americans Pubmed:29427376 |
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J Bas Res Med Sci |
Decreased level of the anti-inflammatory adipokines, secreted frizzled-related protein 5 and adiponectin, in high cholesterol diet-induced atherosclerotic rats article-1-352-en.pdf |
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Molecular Biology Reports |
The effect of serum and follicular fluid secreted frizzle-related protein-5 on in vitro fertilization outcomes in patients with polycystic ovary syndrome Pubmed: 30194556 |
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Macrophage LRP1 promotes diet-induced hepatic inflammation and metabolic dysfunction by modulating Wnt signaling |
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British Journal Of Nutrition |
A diet high in sugar-sweetened beverage and low in fruits and vegetables is associated with adiposity and a pro-inflammatory adipokine profile Pubmed: 30375290 |
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J Clin Endocrinol Metab |
Role of wnt5a in Metabolic Inflammation in Humans Pubmed: 30137542 |
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Frontiers in Endocrinology |
Association of Adipocytokines With Carotid Intima Media Thickness and Arterial Stiffness in Obstructive Sleep Apnea Patients Pubmed: 32300333 |
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CLINICAL BIOCHEMISTRY |
Sfrp5/Wnt5a and Leptin/adiponectin levels in the serum and the periarterial adipose tissue of patients with peripheral arterial occlusive disease Pubmed: 33188773 |
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Sao Paulo Medical Journal |
Association of serum levels of secreted frizzled-related protein 5 and Wnt member 5a with glomerular filtration rate in patients with type 2 diabetes mellitus and … Pubmed: 32491086 |
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Kidney Blood Press Res |
Secreted Frizzled-Related Protein 5 Ameliorates Vascular Calcification in a Rat Model of Chronic Kidney Disease through the Wnt/β-Catenin Pathway 34469882 |
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Cytokine |
Association of serum uromodulin with adipokines in dependence of type 2 diabetes 34920231 |
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PLoS One |
Association of circulating MR-proADM with all-cause and cardiovascular mortality in the general population: Results from the KORA F4 cohort study Pubmed:34990470 |
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JMIR Res Protoc |
Investigating New Sensory Methods Related to Taste Sensitivity, Preferences, and Diet of Mother-Infant Pairs and Their Relationship With Body Composition … Pubmed:35475790 |
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Diabetology |
Early Pregnancy Serum Concentration of Secreted Frizzled-Related Protein 4, Secreted Frizzled-Related Protein 5, and Chemerin in Obese Women Who Develop … |
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Catalog No. |
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Applications (RESEARCH USE ONLY!) |
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WB; IHC; ICC; IP. |
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WB; IHC; ICC. |
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WB; IHC; ICC; IP. |
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LAC842Hu72 |
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WB; IHC; ICC. |
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SEC842Hu |
Enzyme-linked immunosorbent assay for Antigen Detection. |
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WEC842Hu |
Wide-range ELISA Kit for Secreted Frizzled Related Protein 5 (SFRP5) |
Enzyme-linked immunosorbent assay for Antigen Detection. |
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HEC842Hu |
High Sensitive ELISA Kit for Secreted Frizzled Related Protein 5 (SFRP5) |
Enzyme-linked immunosorbent assay for Antigen Detection. |
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LMC842Hu |
Magnetic Luminex Assay Kit for Secreted Frizzled Related Protein 5 (SFRP5) ,etc. |
Magnetic Luminex Assay for Antigen Detection. |
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