Cloud-clone
SKU(재고 관리 코드):MAE912Hu22
Monoclonal Antibody to Sirtuin 1 (SIRT1)
Monoclonal Antibody to Sirtuin 1 (SIRT1)
Western blotting: 0.5-5ug/ml
;Immunocytochemistry in formalin fixed cells: 5-30ug/ml
;Immunohistochemistry in formalin fixed frozen section: 5-30ug/ml
;Immunohistochemistry in paraffin section: 5-30ug/ml
;Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
;Optimal working dilutions must be determined by end user.
Product No.
MAE912Hu22
Organism Species
Homo sapiens (Human).
Source
Monoclonal antibody preparation
Host
Mouse
Potency (Clone Number)
C2
Ig Isotype
IgG1 Kappa
Purification
Protein A + Protein G affinity chromatography
Label
None
Immunogen
RPE912Hu01-Recombinant Sirtuin 1 (SIRT1)
Buffer Formulation
0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Traits
Liquid
Concentration
1mg/mL
Organism Species More
Mus musculus (Mouse), Rattus norvegicus (Rat)
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a mouse monoclonal antibody raised against SIRT1. It has been selected for its ability to recognize SIRT1 in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.5-5ug/ml
Immunocytochemistry in formalin fixed cells: 5-30ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-30ug/ml
Immunohistochemistry in paraffin section: 5-30ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Magazine |
Citations |
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PLoS One. |
SIRT1 Gene Polymorphisms Affect the Protein Expression in Cardiovascular Diseases Plos: Source |
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PLOS ONE |
A Novel Role for SIRT-1 in L-Arginine Protection against STZ Induced Myocardial Fibrosis in Rats Pubmed:25501750 |
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Journal of Alzheimer's Disease |
Serum miR-206 and miR-132 as Potential Circulating Biomarkers for Mild Cognitive Impairment Pubmed:25589731 |
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Respirology |
Increases in peripheral SIRT1: A new biological characteristic of asthma PubMed: 26040995 |
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PLOS ONE |
A Remarkable Age-Related Increase in SIRT1 Protein Expression against Oxidative Stress in Elderly: PubMed: 25785999 |
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Endocrine |
Changes of serum Mir-217 and the correlation with the severity in type 2 diabetes patients with different stages of diabetic kidney disease. pubmed:27522360 |
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Naunyn Schmiedebergs Arch Pharmacol |
The potential curative effect of rebamipide in hepatic ischemia/reperfusion injury pubmed:28361247 |
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International journal of cardiology |
A sirtuin 1/MMP2 prognostic index for myocardial infarction in patients with advanced coronary artery disease pubmed:28043667 |
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International Journal of Cardiology |
Serum concentrations and gene expression of sirtuin 1 in healthy and slightly overweight subjects after caloric restriction or resveratrol supplementation: A randomized trial pubmed:28029409 |
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Hepatology International |
Association of SIRT1 gene polymorphism and its expression for the risk of alcoholic fatty liver disease in the Han population pubmed:29189974 |
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Toxicology and Applied Pharmacology |
Sildenafil protects against bile duct ligation induced hepaticfibrosis in rats: Potential role for silent information regulator 1 (SIRT1) pubmed:28974454 |
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Chemico-biological Interactions |
Magnolol protects pancreatic β-cells against methylglyoxal-induced cellular dysfunction pubmed:28919305 |
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Nutrients |
Gene Expression of Sirtuin-1 and Endogenous Secretory Receptor for Advanced Glycation End Products in Healthy and Slightly Overweight Subjects after … Pubmed:30037068 |
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Experimental Gerontology |
Specific alterations in the circulating levels of the SIRT1, TLR4, and IL7 proteins in patients with dementia Pubmed:30071285 |
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Kidney and Blood Pressure Research |
The Kidney Specific Protein myo-Inositol Oxygenase, a Potential Biomarker for Diabetic Nephropathy Pubmed: 30504713 |
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Journal of International Medical Research |
Serum and follicular fluid levels of sirtuin 1, sirtuin 6, and resveratrol in women undergoing fertilization: an observational, clinical study Pubmed: 30556451 |
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BioMed Research International |
Centella asiatica Prevents Increase of Hippocampal Tumor Necrosis Factor-Independently of Its Effect on Brain-Derived Neurotrophic Factor in Rat Model of Chronic … |
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学位论文 |
Influência do tratamento da doença periodontal na sirtuína 1 e na lectina ligadora de manose em indivíduos com doença arterial coronária |
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Journal of Physics D: Applied Physics |
Premature Myocardial Infarction: Genetic Variations in SIRT1 Affect Disease Susceptibility |
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Journal of Geriatric Oncology |
Serum biomarkers for predicting overall survival and early mortality in older patients with metastatic solid tumors Pubmed: 30952517 |
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Biomed Research International |
Prevents Increase of Hippocampal Tumor Necrosis Factor-α Independently of Its Effect on Brain-Derived Neurotrophic Factor in Rat Model of … Pubmed: 30956976 |
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Journal of Diabetes and its Complications |
Vasohibin-1 in T2DM with different UACR |
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Clinical Interventions in Aging |
The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis Pubmed: 32214805 |
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Compr Psychiatry |
Crocin alleviates schizophrenia-like symptoms in rats by upregulating silent information regulator-1 and brain derived neurotrophic factor Pubmed: 33045669 |
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Сибирский федеральный университет |
Влияние гречневой крупы на сиртуиновую активность у подопытных животных в эксперименте |
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Journal of Cereal Science |
Dietary buckwheat enhances sirtuin1 without calorie restriction |
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Clin Interv Aging |
Molecular Changes in Circulating microRNAs' Expression and Oxidative Stress in Adults with Mild Cognitive Impairment: A Biochemical and Molecular Study 33447019 |
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Antioxidants |
The Effect of Repeated Whole-Body Cryotherapy on Sirt1 and Sirt3 Concentrations and Oxidative Status in Older and Young Men Performing Different Levels of?¡ 33396247 |
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Int Urol Nephrol |
Evaluation of sirtuin 1 (SIRT1) levels in autosomal dominant polycystic kidney disease 33864594 |
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Neurochem Int |
Dimethyl fumarate abridged tauo-/amyloidopathy in a D-Galactose/ovariectomy-induced Alzheimer's-like disease: Modulation of AMPK/SIRT-1, AKT/CREB/BDNF, AKT ¡ 34052296 |
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Toxicol Appl Pharmacol |
Prasugrel anti-ischemic effect in rats: Modulation of hippocampal SUMO2/3-IкBα/Ubc9 and SIRT-1/miR-22 trajectories 34174262 |
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Food Chem |
Buckwheat-enriched diet alleviates bisphenol A mediated oxidative stress via modulation of sirtuin 1 and antioxidant status in experimental rats 34763933 |
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Life Sci |
Novel mechanistic insights towards the repositioning of alogliptin in Parkinson's disease 34774622 |
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Int J Mol Sci |
Intralesional Infiltrations of Arteriosclerotic Tissue Cells-Free Filtrate Reproduce Vascular Pathology in Healthy Recipient Rats Pubmed:35163435 |
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J Clin Med |
Effects of Coffee on Sirtuin-1, Homocysteine, and Cholesterol of Healthy Adults: Does the Coffee Powder Matter? Pubmed:35683374 |
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Cell & Bioscience |
OGT Protects Skeletal Muscle From Damage Through SIRT1 O-GlcNAcylation During Cold Stress |
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Catalog No. |
Related products for research use of Homo sapiens (Human) Organism species |
Applications (RESEARCH USE ONLY!) |
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RPE912Hu01 |
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MAE912Hu22 |
WB; IHC; ICC; IP. |
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WB; IHC; ICC; IP. |
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WB; IHC; ICC; IP. |
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SEE912Hu |
Enzyme-linked immunosorbent assay for Antigen Detection. |
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LME912Hu |
Magnetic Luminex Assay for Antigen Detection. |
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PSE912Hu01 |
ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays. |
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KSE912Hu01 |
Main materials for "Do It (ELISA Kit) Yourself". |
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