NCAM-L1(Phospho Ser1181) Polyclonal Antibody

The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain| consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III)| is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development| including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia| retardation| aphasia| spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants| some of which include an alternate exon that is considered to be specific to neurons.

The NCAM-L1(Phospho Ser1181) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of NCAM-L1 protein phosphorylated at Ser1181. This antibody is produced using high-quality polyclonal antibodies that have been carefully selected and validated for their specificity and sensitivity.

NCAM-L1, also known as Neural Cell Adhesion Molecule L1, is a cell surface glycoprotein that plays a crucial role in neuronal development, axon guidance, and synaptic plasticity. Phosphorylation of NCAM-L1 at Ser1181 has been implicated in various cellular processes, including cell adhesion, migration, and signal transduction.

The NCAM-L1(Phospho Ser1181) Polyclonal Antibody has been rigorously tested and validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated NCAM-L1 and other related proteins, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation, making it easy to use and compatible with a wide range of experimental protocols. It is provided in a convenient size and concentration, allowing for multiple experiments and minimizing waste.

In summary, the NCAM-L1(Phospho Ser1181) Polyclonal Antibody is a valuable tool for researchers studying the role of NCAM-L1 phosphorylation in neuronal development and function. Its high specificity, sensitivity, and versatility make it an essential component of any laboratory working in the field of neuroscience.