Neurexin I Polyclonal Antibody

NRXN1 (neurexin 1) encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for NRXN1 in the 3' region. Mutations in NRXN1 are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia.

The Neurexin I Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Neurexin I protein in various biological samples. This antibody has been meticulously developed and validated to ensure exceptional performance and accuracy in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Neurexin I Polyclonal Antibody exhibits a high affinity and specificity towards Neurexin I, a cell adhesion molecule that plays a crucial role in synaptic transmission and neuronal development. With its exceptional sensitivity, this antibody enables the detection of even low levels of Neurexin I protein, facilitating precise quantification and analysis.

This antibody has been rigorously tested and validated to ensure consistent and reproducible results. It exhibits minimal cross-reactivity with other proteins, ensuring reliable and specific detection of Neurexin I. Furthermore, it demonstrates excellent stability and long shelf life, allowing for reliable and consistent performance over time.

The Neurexin I Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and complex preparation steps. Its user-friendly format enables convenient and efficient usage, saving valuable time and resources in the laboratory.

In summary, the Neurexin I Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of Neurexin I protein. With its exceptional sensitivity, stability, and user-friendly format, this antibody is an invaluable asset for researchers and scientists working in the field of neuroscience and synaptic transmission.