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Dima Biotech

SKU(재고 관리 코드):PME100655

Human FOLR2 Protein, His Tag

Human FOLR2 Protein, His Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

BETA-HFR;FBP;FBP/PL-1;FOLR1;FR-BETA;FR-P3;FRbeta

DESCRIPTION

Recombinant human FOLR2 protein with C-terminal 6×His tag

DELIVERY

In Stock

UNIPROT ID

P14207

EXPRESSION HOST

HEK293

TAG

C-6×His Tag

MOLECULAR CHARACTERIZATION

FOLR2(Thr17-His228) 6×His tag

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 25.4 kDa after removal of the signal peptide. The apparent molecular mass of FOLR2-His is approximately 25-35 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

USAGE

Research use only

IMAGES

sp-PME100655 FOLR2 His PAGE 300

Figure 1. Human FOLR2 Protein, His Tag on SDS-PAGE under reducing condition.
elisa-PME100655 FOLR2 Fig.2 Elisa 1
Figure 2. ELISA plate pre-coated by 4 μg/mL (100 μL/well) Human FOLR2 Protein, His Tag(PME100655) can bind Anti-FOLR2 antibody(DMC390), IgG1 Chimeric mAb in a linear range of 0.64–16 ng/mL.

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