제품 정보로 건너뛰기
1 1

Dima Biotech

SKU(재고 관리 코드):PME100671

Human RSPO3 (22-146) Protein, hFc Tag

Human RSPO3 (22-146) Protein, hFc Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

CRISTIN1;PWTSR;THSD2

DESCRIPTION

Recombinant human RSPO3(22-146) protein with C-terminal human Fc tag

DELIVERY

In Stock

UNIPROT ID

Q9BXY4

EXPRESSION HOST

HEK293

TAG

C-Human Fc Tag

MOLECULAR CHARACTERIZATION

RSPO3(22-146)(Ser19-Glu351) hFc(Glu99-Ala330)

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 38.6 kDa after removal of the signal peptide. The apparent molecular mass of RSPO3(22-146)-hFc is approximately 35-55 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013]

USAGE

Research use only

IMAGES

sp-PME100671 RSPO322 146 hFc PAGE 300

Figure 1. Human RSPO3(22-146) Protein, hFc Tag on SDS-PAGE under reducing condition.

전체 세부 정보 보기