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Dima Biotech

SKU(재고 관리 코드):PME100010

Human 2B4 Protein, mFc-His Tag

Human 2B4 Protein, mFc-His Tag

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통합 견적 요청
Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

CD244;2B4;SLAMF4;NKR2B4;NAIL;h2B4

DESCRIPTION

Recombinant human 2B4 protein with C-terminal mouse Fc and 6×His tag

DELIVERY

In Stock

UNIPROT ID

Q9BZW8

EXPRESSION HOST

HEK293

TAG

C-Mouse Fc and 6×His Tag

MOLECULAR CHARACTERIZATION

2B4(Cys22-Ala221) mFc(Pro99-Lys330) 6×His

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 48.8 kDa after removal of the signal peptide. The apparent molecular mass of 2B4-mFc-His is approximately 70-100 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

USAGE

Research use only

IMAGES

sp-PME100010 2B4 mFc His PAGE 300

Figure 1. Human 2B4, mFc-His Tag on SDS-PAGE under reducing condition.

elisa-PME100010 2B4 mFc His ELISA Fig2

Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human 2B4, mFc-His tagged protein (PME100010) can bind Human CD48, hFc tagged protein (PME100476) in a linear range of 31.25-4000 ng/ml.

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