| TARGET | |
|---|---|
| SYNONYMS |
TNFSF18;AITRL;TL6;hGITRL;GITR Ligand |
| DESCRIPTION |
Recombinant human GITR Ligand protein with N-terminal mouse Fc and C-terminal 6×His tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q9UNG2 |
| EXPRESSION HOST |
HEK293 |
| TAG |
N-Mouse Fc and C-6×His Tag |
| MOLECULAR CHARACTERIZATION |
mFc(Pro99-Lys330) GITR Ligand(Gln50-Ser177) 6×His |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 46-53 kDa after removal of the signal peptide. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME100020
Human GITR Ligand Protein, mFc-His tag
Human GITR Ligand Protein, mFc-His tag
PRODUCT DATA
IMAGES
Figure 1. Human GITR Ligand Protein, mFc-His Tag on SDS-PAGE under reducing condition.
Figure 2. Flow cytometry analysis with 1 μg/mL Human GITRL Protein, mFc-His tag (PME100020) on Expi293 cells transfected with human GITR (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
