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Dima Biotech

SKU(재고 관리 코드):PME100027

Human CD155 Protein, mFc-His tag

Human CD155 Protein, mFc-His tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

PVR;FLJ25946;PVS;CD155;TAGE4;HVED;NECL5

DESCRIPTION

Recombinant human CD155 protein with C-terminal mouse Fc and 6×His tag

DELIVERY

In Stock

UNIPROT ID

P15151

EXPRESSION HOST

HEK293

TAG

C-Mouse Fc and 6×His Tag

MOLECULAR CHARACTERIZATION

CD155(Trp21-Asn343) mFc(Pro99-Lys330) 6×His tag

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 62.2 kDa after removal of the signal peptide. The apparent molecular mass of CD155-mFc-His is approximately 95-130 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

USAGE

Research use only

IMAGES

sp-PME100027 SP CD155 300

Figure 1. Human CD155 Protein, mFc-His Tag on SDS-PAGE under reducing condition.

elisa-PME100027 CD155 mFc His ELISA Fig2

Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human CD155, mFc-His tagged protein (PME100027) can bind Human TIGIT, hFc tagged protein (PME100107) in a linear range of 1.95-125 ng/ml.

elisa-PME100027 CD155 mFc His ELISA Fig3

Figure 3. ELISA plate pre-coated by 1 μg/mL (100 μL/well) Human CD155 Protein, mFc-His Tag(PME100027) can bind Anti-CD155 Rabbit mAb in a linear range of 3.2-80 ng/mL.

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