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Dima Biotech

SKU(재고 관리 코드):PME100463

Human TweakR Protein, mFc Tag

Human TweakR Protein, mFc Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

TNFRSF12A;GF-inducible 14;N14;weakR;D266

DESCRIPTION

Recombinant human TweakR protein with C-terminal mouse Fc tag

DELIVERY

In Stock

UNIPROT ID

Q9NP84

EXPRESSION HOST

HEK293

TAG

C-Mouse Fc Tag

MOLECULAR CHARACTERIZATION

TweakR(Glu28-Pro80) mFc(Pro99-Lys330)

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 31.8 kDa after removal of the signal peptide.

PURITY

The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

TNFRSF12A (TNF Receptor Superfamily Member 12A) is a Protein Coding gene. Diseases associated with TNFRSF12A include?Multiple Sclerosis?and?Stroke, Ischemic. Among its related pathways are?ERK Signaling?and?CDK-mediated phosphorylation and removal of Cdc6

USAGE

Research use only

IMAGES

sp-PME100463 TweakR mFc SP

Figure 1. Human TweakR Protein, mFc Tag on SDS-PAGE under non-reducing (NR) and reducing (R) conditions.

elisa-PME100463 TweakR mFc ELISA Fig2

Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human TweakR, mFc tagged protein (PME100463) can bind Anti-TweakR Neutralizing antibody (BME100031) in a linear range of 0.64-80 ng/ml.

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