| TARGET | |
|---|---|
| SYNONYMS |
DNAM1;CD226;PTA1 |
| DESCRIPTION |
Recombinant human DNAM-1 protein with C-terminal mouse Fc and 6×His tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q15762 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-Mouse Fc and 6×His Tag |
| MOLECULAR CHARACTERIZATION |
DNAM-1(Glu19-Asn247) mFc(Pro99-Lys330) 6×His tag |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 53.5 kDa after removal of the signal peptide. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME100050
Human DNAM-1 Protein, mFc-His Tag
Human DNAM-1 Protein, mFc-His Tag
PRODUCT DATA
IMAGES
Figure 1. Human DNAM-1 Protein, mFc-His Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human DNAM-1, mFc-His tagged protein (PME100050) can bind Human CD155, hFc Tagged protein (PME100485) in a linear range of 0.128-32.88 ng/ml.
