| TARGET | |
|---|---|
| SYNONYMS |
EPCAM;ACSTD1;ROP1;D326;IAR5;GP2;GP314;GP40;SA;A733-2;NPCC8;NPCC-8;S1/4;SA;4S1;IC18;K1 |
| DESCRIPTION |
Recombinant human EPCAM protein with C-terminal 6×His tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
P16422 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-6×His Tag |
| MOLECULAR CHARACTERIZATION |
EPCAM(Gln24-Lys265) 6×His tag |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 28.2 kDa after removal of the signal peptide. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME100068
Human EPCAM Protein, His Tag
Human EPCAM Protein, His Tag
PRODUCT DATA
IMAGES
Figure 1. Human EPCAM Protein, His Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human EPCAM Protein, His Tag (PME100068) can bind Anti-EPCAM antibody(DM147), Rabbit mAb in a linear range of 3.20–16 ng/mL.
Figure 3. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human EPCAM Protein, His Tag (PME100068) can bind Anti-EPCAM(oportuzumab biosimilar) mAb (BME100184) in a linear range of 0.64–16 ng/mL.
