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Dima Biotech

SKU(재고 관리 코드):PME100068

Human EPCAM Protein, His Tag

Human EPCAM Protein, His Tag

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통합 견적 요청
Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

EPCAM;ACSTD1;ROP1;D326;IAR5;GP2;GP314;GP40;SA;A733-2;NPCC8;NPCC-8;S1/4;SA;4S1;IC18;K1

DESCRIPTION

Recombinant human EPCAM protein with C-terminal 6×His tag

DELIVERY

In Stock

UNIPROT ID

P16422

EXPRESSION HOST

HEK293

TAG

C-6×His Tag

MOLECULAR CHARACTERIZATION

EPCAM(Gln24-Lys265) 6×His tag

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 28.2 kDa after removal of the signal peptide.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.

USAGE

Research use only

IMAGES

sp-PME100068 EPCAM His SP

Figure 1. Human EPCAM Protein, His Tag on SDS-PAGE under reducing condition.

elisa-PME100068 EPCAM His ELISA Fig2

Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human EPCAM Protein, His Tag (PME100068) can bind Anti-EPCAM antibody(DM147), Rabbit mAb in a linear range of 3.20–16 ng/mL.
sp-PME100068 EPCAM Fig.3 Elisa 2
Figure 3. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human EPCAM Protein, His Tag (PME100068) can bind Anti-EPCAM(oportuzumab biosimilar) mAb (BME100184) in a linear range of 0.64–16 ng/mL.

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