| TARGET | |
|---|---|
| SYNONYMS |
TNFRSF10B;RAILR2;RAIL-R2;D262;R5;ILLER;RICK2;TNFR9;RICKB |
| DESCRIPTION |
Recombinant human TNFRSF10B protein with C-terminal mouse Fc tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
O14763 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-Mouse Fc Tag |
| MOLECULAR CHARACTERIZATION |
TNFRSF10B (Ile56-Glu186) mFc(Pro99-Lys330) |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 40.5 kDa after removal of the signal peptide. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME100465
Human TNFRSF10B Protein, mFc Tag
Human TNFRSF10B Protein, mFc Tag
PRODUCT DATA
IMAGES
Figure 1. Human TNFRSF10B Protein, mFc Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human TNFRSF10B, mFc tagged protein (PME100465) can bind Anti-TNFRSF10B Neutralizing antibody (BME100032) in a linear range of 3.2-80 ng/ml.
