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Dima Biotech

SKU(재고 관리 코드):PME100070

Human AXL Protein, His Tag

Human AXL Protein, His Tag

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통합 견적 요청
Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

AXL;FO

DESCRIPTION

Recombinant human AXL protein with C-terminal 6×His tag

DELIVERY

In Stock

UNIPROT ID

P30530

EXPRESSION HOST

HEK293

TAG

C-6×His Tag

MOLECULAR CHARACTERIZATION

AXL(Ala26-Pro449) 6×His tag

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 46.6 kDa after removal of the signal peptide.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.

USAGE

Research use only

IMAGES

sp-PME100070 AXL His SP

Figure 1. Human AXL Protein, His Tag on SDS-PAGE under reducing condition.

elisa-PME100070 AXL His ELISA Fig2

Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human AXL, His tagged protein (PME100070) can bind Anti-AXL Antibody (BME100033) in a linear range of 0.64-80.0 ng/ml.

elisa-PME100070 AXL His ELISA Fig3

Figure 3. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human AXL, His tagged protein (PME100070) can bind Human NTD, mFc Tagged protein (PME100492) in a linear range of 0.006-0.16 μg/ml.

elisa-PME100070 AXL His ELISA Fig4

Figure 4. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human AXL, His tagged protein (PME100070) can bind Human NTD, hFc Tagged protein (PME100493) in a linear range of 0.0012-0.16 μg/ml.

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