| TARGET | |
|---|---|
| SYNONYMS |
ICOS;CD278;AILIM;Inducible T-cell costimulator |
| DESCRIPTION |
Recombinant human ICOS protein with C-terminal human Fc tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q9Y6W8 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-Human Fc Tag |
| MOLECULAR CHARACTERIZATION |
ICOS(Glu21-Lys140) hFc(Glu99-Ala330) |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 39.7 kDa after removal of the signal peptide. The apparent molecular mass of ICOS-hFc is approximately 55 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME100484
Human ICOS Protein, hFc tag
Human ICOS Protein, hFc tag
PRODUCT DATA
IMAGES
Figure 1. Human ICOS Protein, hFc Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 1 μg/mL (100 μL/well) Human ICOS protein, hFc Tag (PME100484) can bind Anti-ICOS Neutralizing antibody (BME100012) in a linear range of 0.64-400 ng/mL.
