TARGET | |
---|---|
SYNONYMS |
PSCA;NQ206;RO232 |
DESCRIPTION |
Recombinant human PSCA protein with C-terminal human Fc |
DELIVERY |
In Stock |
UNIPROT ID |
O43653 |
EXPRESSION HOST |
HEK293 |
TAG |
C-Human Fc Tag |
MOLECULAR CHARACTERIZATION |
PSCA(Leu12-Ser86) hFc(Glu99-Ala330) |
MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 34.4 kDa after removal of the signal peptide.The apparent molecular mass of PSCA-hFc is approximately 40-57 kDa due to glycosylation. |
PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals, this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. |
USAGE |
Research use only |
SKU(재고 관리 코드):PME100084
Human PSCA Protein, hFc Tag
Human PSCA Protein, hFc Tag
PRODUCT DATA
IMAGES
Figure 1. Human PSCA Protein, hFc Tag on SDS-PAGE under reducing condition