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Dima Biotech

SKU(재고 관리 코드):PME100097

Human ROR2 Protein, His Tag

Human ROR2 Protein, His Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

ROR2;TRKR2

DESCRIPTION

Recombinant human ROR2 Protein with C-terminal 6×His tag

DELIVERY

In Stock

UNIPROT ID

Q01974

EXPRESSION HOST

HEK293

TAG

C-6×His Tag

MOLECULAR CHARACTERIZATION

ROR2(Glu34-Gly403) 6×His tag

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 42.2 kDa after removal of the signal peptide.The apparent molecular mass of ROR2-His is approximately 55-70 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.

USAGE

Research use only

IMAGES

sp-PME100097 ROR2 His PAGE 300

Figure 1. Human ROR2 Protein, His Tag on SDS-PAGE under reducing condition.

elisa-PME100097 ROR2 His ELISA Fig2

Figure 2. ELISA plate pre-coated by 1 μg/mL (100 μL/well) Human ROR2 protein, His Tag (PME100097) can bind Anti-ROR2 Rabbit mAb in a linear range of 0.128-16 ng/mL.

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