| TARGET | |
|---|---|
| SYNONYMS |
IL2RA;D25;55;L2-RA;L-2-RA |
| DESCRIPTION |
Recombinant human IL2RA Protein with C-terminal 6×His tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
P01589 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-6×His Tag |
| MOLECULAR CHARACTERIZATION |
IL2RA(Glu22-Cys213) 6×His tag |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 22.6 kDa after removal of the signal peptide.The apparent molecular mass of IL2RA-His is approximately 35-55 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME100098
Human IL2RA Protein, His Tag
Human IL2RA Protein, His Tag
PRODUCT DATA
IMAGES
Figure 1. Human IL2RA Protein, His Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human IL2RA, His tagged protein (PME100098) can bind Anti-IL2RA Neutralizing antibody (BME100043) in a linear range of 0.64-400 ng/ml.
Figure 3. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human IL2RA Protein, His Tag (PME100098) can bind Human IL2 Protein, hFc Tag (PME100300) in a linear range of 0.64-400 ng/mL
