| TARGET | |
|---|---|
| SYNONYMS |
AAT5;ACVRLK4;ALK-5;ALK5;ESS1;LDS1;LDS1A;LDS2A;MSSE;SKR4;tbetaR-I;TBR-i;TBRI;TGFR-1 |
| DESCRIPTION |
Recombinant human TGFBR1 Protein with N-terminal Human Fc tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
P36897 |
| EXPRESSION HOST |
HEK293 |
| TAG |
N-Human Fc Tag |
| MOLECULAR CHARACTERIZATION |
hFc(Glu99-Ala330) TGFBR1(Leu34-Leu126) |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 36.3 kDa after removal of the signal peptide.The apparent molecular mass of hFc-TGFBR1 is approximately 40-53 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME100103
Human TGFBR1 Protein, N-hFc Tag
Human TGFBR1 Protein, N-hFc Tag
PRODUCT DATA
IMAGES
Figure 1. Human TGFBR1 Protein, N-hFc Tag on SDS-PAGE under reducing condition
