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Dima Biotech

SKU(재고 관리 코드):PME100820

Human CXCR1 Protein, hFc Tag

Human CXCR1 Protein, hFc Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

C-C;C-C-CKR-1;CD128;CD181;CDw128a;CKR-1;CMKAR1;IL8R1;IL8RA;IL8RBA

DESCRIPTION

Recombinant human CXCR1 protein with C-terminal human Fc tag

DELIVERY

In Stock

UNIPROT ID

P25024

EXPRESSION HOST

HEK293

TAG

C-Human Fc Tag

MOLECULAR CHARACTERIZATION

CXCR1(Met1-Lys39) hFc(Glu99-Ala330)

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 30.6 kDa after removal of the signal peptide. The apparent molecular mass of CXCR1-hFc is approximately 40-55 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008]

USAGE

Research use only

IMAGES

sp-PME100820 CXCR1 hFc PAGE 300

Figure 1. Human CXCR1 Protein, hFc Tag on SDS-PAGE under reducing condition

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