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Dima Biotech

SKU(재고 관리 코드):PME100821

Human MST1R Protein, hFc Tag

Human MST1R Protein, hFc Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

CD136;CDw136;NPCA3;PTK8;RON

DESCRIPTION

Recombinant Human MST1R Protein with C-terminal Human Fc tag

DELIVERY

In Stock

UNIPROT ID

Q04912

EXPRESSION HOST

HEK293

TAG

C-Human Fc Tag

MOLECULAR CHARACTERIZATION

MST1R(Glu25-Thr957) hFc(Glu99-Ala330)

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 125.9 kDa after removal of the signal peptide. The apparent molecular mass of MST1R-hFc is approximately 130-250 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016]

USAGE

Research use only

IMAGES
sp-PME100821 MST1R hFc PAGE 300

Figure 1. Human MST1R Protein, hFc Tag on SDS-PAGE under reducing condition.

elisa-PME100821 MST1R hFc ELISA Fig2

Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human MST1R Protein, hFc Tag (PME100821) can bind Anti-MST1R Neutralizing antibody (BME100118) in a linear range of 0.73–46.88 ng/mL

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