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Dima Biotech

SKU(재고 관리 코드):PME100822

Human CEACAM6 Protein, His Tag

Human CEACAM6 Protein, His Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

CD66c;CEAL;NCA

DESCRIPTION

Recombinant human CEACAM6 protein with C-terminal 6×His tag

DELIVERY

In Stock

UNIPROT ID

P40199

EXPRESSION HOST

HEK293

TAG

C-6×His Tag

MOLECULAR CHARACTERIZATION

CEACAM6(Lys35-Gly320) 6×His tag

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 32.1 kDa after removal of the signal peptide. The apparent molecular mass of CEACAM6-His is approximately 35-55 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014]

USAGE

Research use only

IMAGES

sp-PME100822 CEACAM6 His PAGE 300

Figure 1. Human CEACAM6 Protein, His Tag on SDS-PAGE under reducing condition.

elisa-PME100822 CEACAM6 His ELISA Fig2

Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CEACAM6 Protein, His Tag (PME100822) can bind Anti-CEACAM6 Neutralizing antibody (BME100100) in a linear range of 0.61–156.25 ng/mL

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