| TARGET | |
|---|---|
| SYNONYMS |
CD127;CDW127;IL-7R-alpha;IL7RA;ILRA |
| DESCRIPTION |
Recombinant Human IL7RA with C-terminal human Fc tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
P16871 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-Human Fc Tag |
| MOLECULAR CHARACTERIZATION |
IL7RA(Glu21-Gly236) hFc(Glu99-Ala330) |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 51.0 kDa after removal of the signal peptide.The apparent molecular mass of IL7RA-hFc is approximately 55-100 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015] |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME100840
Human IL7RA Protein, hFc Tag
Human IL7RA Protein, hFc Tag
PRODUCT DATA
IMAGES
Figure 1. Human IL7RA Protein, hFc Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human IL7RA Protein, hFc Tag(PME100840) can bind Anti-IL7RA antibody(DMC272), IgG1 Chimeric mAb in a linear range of 3.20–80 ng/mL.
