| TARGET | |
|---|---|
| SYNONYMS |
IL-13;NC30 |
| DESCRIPTION |
Recombinant human IL13 protein with C-terminal human Fc tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
P35225 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-Human Fc Tag |
| MOLECULAR CHARACTERIZATION |
IL13(Thr21-Leu132) hFc(Glu99-Ala330) |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 38.1 kDa after removal of the signal peptide. The apparent molecular mass of IL13-hFc is approximately 35-70 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008] |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME100872
Human IL13 Protein, hFc Tag
Human IL13 Protein, hFc Tag
PRODUCT DATA
IMAGES
Figure 1. Human IL13 Protein, hFc Tag on SDS-PAGE under reducing condition
