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Dima Biotech

SKU(재고 관리 코드):PME100555

Human IL21 Protein, mFc Tag

Human IL21 Protein, mFc Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

IL21;a11;nterleukin-21

DESCRIPTION

Recombinant Human IL21 with C-terminal mouse Fc tag

DELIVERY

In Stock

UNIPROT ID

Q9HBE4

EXPRESSION HOST

HEK293

TAG

C-Mouse Fc Tag

MOLECULAR CHARACTERIZATION

IL21(Gln30-Ser162) mFc(Pro99-Lys330)

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 41.6 kDa after removal of the signal peptide.The apparent molecular mass of IL21-mFc is approximately 35-55 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

USAGE

Research use only

IMAGES

sp-PME100555 IL21 mFc PAGE 300

Figure 1. Human IL21 Protein, mFc Tag on SDS-PAGE under reducing condition

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